I also have been through every med out there and none work for me except Remicade but I built up antibodies to it and had to stop. 6mp was messing up my liver, nothing was working so my doc said lets try Methotrexate. Like another poster said it's not a quick fix takes about 2 or 3 months to kick in. But you definitely want to inject it. The only side affect I get from it is tired. It make me tired and sleepy for about a day and half after my one week injection. So I take it on Fridays and gives me the weekend to rest. For me, I don't think it's working 100 percent but it does help some so far. I would try everything before surgery. Good luck, this disease is bad stuff no doult!
Have been on weekly injections for 15 months with no side effects. I can't see the side effects any more scary than being on Remicade, Humira or any length of Prednisone.
You will have to have regular bloodwork done so this will detect any harm it could be doing in it's early stage.
Post Edited (karasmommy) : 12/31/2009 6:25:48 PM (GMT-7)