I've been on methotrexate for about a month and a half - you may want to wait to see if the side effects decrease with time. I was scared to death of my first 2 doses, and I was a little sleepy and nauseous the next day. I haven't seen any problems at all with my last few doses, and I think it's really helping the Crohn's.
I snack on crystallized ginger and ginger tea if I'm nauseous, which helps.
Best of luck!