The WavSTAT Optical Biopsy System, uses the principle of Laser Induced Fluorescence (LIF). Diseased or cancerous tissue fluoresces differently compared to normal healthy tissue. Diseased tissue has reduced fluorophors which, when analyzed by a specialized detector, can indicate with high sensitivity that the cells are becoming dysplastic, a precursor to cancer. During colonoscopy, a small fiber-optic probe is directed by the clinician to touch the suspicious tissue. Depressing a foot switch directs low powered, safe laser light into the tissue. The laser shuts off and the tissue fluorescence light is directed back up the same fiber optic probe to a specialized detector. The system's computer analyzes the detector's output and, within seconds, displays a RED or GREEN light on a screen. A GREEN light means the tissue is "normal" with 96% sensitivity. Where a flat polyp is suspect, multiple uses of the optical fiber and the RED light may assist the clinician in determining the margin of the "suspect" tissue and remove all of it in the same procedure. The WavSTAT has been approved by the FDA for detecting pre-cancerous and cancerous tissue in the colon.
SpectraScience is a San Diego based medical device company that designs, develops, manufactures and markets spectrophotometry systems capable of determining whether tissue is normal, pre-cancerous or cancerous, without physically removing tissue from the body.
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