my remicade predicament.

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Regular Member

Date Joined Jan 2010
Total Posts : 448
   Posted 2/9/2010 11:38 AM (GMT -6)   
So i have been on remicade for a little less than a year.
It doesnt seem to bulk my diarrhea but always takes the pain away and lets me eat more.

I want to try MTX because i really want to try for remission which i never have had.

My doctor says once i stop remicade there is no going back.

Should i do both or just MTX?

I asked them and i should hear back 2morrow.

Any increased risk?

Rider Fan
Veteran Member

Date Joined May 2008
Total Posts : 1445
   Posted 2/9/2010 11:39 AM (GMT -6)   
I doubt MTX would be more effective than Remicade. I've heard of some people being on both.
33 y/o male. Dx'ed in 1999. No surgeries.

Current meds: Humira 2/27/09. Proferrin iron pills.

Tried SCD, didn't work, now avoiding gluten and dairy.

Go Saskatchewan Roughriders!

Veteran Member

Date Joined Aug 2007
Total Posts : 1202
   Posted 2/9/2010 12:57 PM (GMT -6)   
I agree completely with Rider. As someone who stopped Remicade and lost it forever, I would add MTX and go from there. You can stop it later if it seems appropriate. This way you keep Remicade while understanding if MTX helps. Good luck!
1 fistula, crohn's colitis, limited to large intestine
Compounded budesonide 3mg/daily, Cimzia, MTX . Dx Osteoporosis 10/08 started Forteo 1/27/09

Regular Member

Date Joined Jan 2010
Total Posts : 448
   Posted 2/9/2010 2:20 PM (GMT -6)   
Thx u both. I have been through SO MUCH like we all have, and right now after 10 years... id rather just go for it all. But i honestly just want to know the Added risk or difference. Mtx is ALL i have left.

Regular Member

Date Joined Apr 2009
Total Posts : 382
   Posted 2/9/2010 2:59 PM (GMT -6)   
they usually give methotrexate in order to prevent you from developing antibodies to remicade, but some people are using it as monotherapy. I believe using methotrexate in combination with remicade is less safe when you're looking at risk of infections and secondary malignancies. This is definitely true with using imuran along with Remicade. I am getting this information from Clinical Pharmacology.
Crohn's Colitis diagnosed 6/08
Organic SCD since 4/09
Remicade since 6/09
Boswellia + Natren's Healthy Trinity probiotic + Cinnamon + Wild Oregano Oil + vitamin D + zinc + Barlean's fish oil

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