I've been on Remicade since October, and I've found that it's been a process of trial and error to see what schedule/dosage works best for me. My doctor did a blood test (I think it was Prometheus, or something like that) right before my last treatment and she said that there was virtually no evidence of the Remicade in my system. That, combined with the results of my latest colonoscopy, made her decide to double my dosage for my next infusion, which is tomorrow morning. She's also still considering putting me on a four-week schedule versus the eight-week schedule I'm currently on.
I'm like you - I tend to feel better right away and have fewer bouts of D right after my infusions, but after a few weeks, my symptoms go back to "normal." My advice is to talk to your doc about what you're experiencing, maybe get some blood tests to measure your levels at various times in your treatment cycle, and work with your doc to adjust your treatment to optimally help your disease.
Thankful every day for my cats, Marley and Mickey - the best bathroom entertainment in the world!
Diagnosed with Crohn's at age 19, October 1999.
Small bowel resection, April 2000.
Current meds: Remicade (10 mg/kg every 8 weeks), 6MP (just started phasing in; currently at 25 mg/day), Entocort (phasing out; 3 mg/day), Lexapro, TriNessa, Digestive Advantage Crohn's & Colitis daily supplement, multivitamin, B-12 supplement, daily anti-diarrheal pill