Debilitated you need to talk to your doctor about
this. His recommendation has been MTX. Why can't you take both together? You are already on a VERY strong pain med that causes drowsiness by itself. The MTX only causes the drowsiness for the day afterwards is what I have heard. Take it like some of the others do on a Friday evening, that way you have the weekend to recuperate. Zofran does NOT make you drowsy, it will just help with any nausea you might have.
Gail*Nanners* Co-Moderator for Crohns Disease & Anxiety/Panic
Crohn's Disease for over 34 years. Currently on Asacol, Prilosec, Estrace, Prinivil, Diltiazem, Percoset prn for pain, Zofran, Phenergan, Probiotics, Calcium, Vit D, and Xanax prn. Resections in 2002 & 2005. Also diagnosed w/ Fibromyalgia, Osteoarthritis, & Anxiety. Currently my Crohns is in remission, but my joints are going crazy!