My daughter had a routine appt. today with her (new) GI. Long story short, she's recommending getting off Pentasa altogether, and after a Metabolite test, increasing her Imuran by 25mgs.
She has been doing well for sometime now, which I know is not necessarily and exact science for the future. I felt uncomfortable tampering with her current formula, so she agreed to leave things status quo for now, and re-assess in 4 months.
She does admit to some evidence of Pentasa and Imuran working well synergistically, but in general does not feel Pentasa is a worthwhile drug.
The Imuran is only slighty under the optimum theraputic level, so is likely still effective at the current dosage.
Does anyone have an opinion, or advise on this?
My daughter was diagnosed Feb. 19/07, (13 yrs. old at time of diagnosis), with Crohn's of the Terminal Illium. Has used Prednisone and Pentasa. Started Imuran (02/09), had an abdominal abscess (12/08). 2cm of Stricture.