Is a normal SED rate normal when you have Crohn's

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Regular Member

Date Joined Dec 2008
Total Posts : 73
   Posted 4/6/2010 10:30 AM (GMT -6)   
My PCP ordered blood work as part of my physical, including my SED rate. I just called to get the results and my SED rate is normal! So.......does that mean I have no inflammation or is the test result NOT a good indicator of what is really going on inside the bowel? Anyone know?
Diagnosed with Crohn's this year at age 38.

Veteran Member

Date Joined Aug 2007
Total Posts : 1202
   Posted 4/6/2010 10:35 AM (GMT -6)   
It's always represented pretty well for me... Meaning, last time it was within normal range was the last time I had no disease activity. I think CRP is a more accurate marker since it changes more quickly in response to changes in inflammation, but my GI does sed rate.
1 fistula, crohn's colitis, limited to large intestine
Compounded budesonide 3mg/daily, Cimzia, MTX . Dx Osteoporosis 10/08 started Forteo 1/27/09

Post Edited (sr5599) : 4/6/2010 9:39:24 AM (GMT-6)

Regular Member

Date Joined Oct 2009
Total Posts : 157
   Posted 4/6/2010 11:21 AM (GMT -6)   
I know that it takes quite awhile after you start feeling bad for the SED rate to elevate. Like sr5599 said, the CRP levels are a better marker. I've had flares with a normal SED rate but elevated WBCs and CRP levels.
If you feel like crap, then you feel like crap. No blood test is going to change that. If you FEEL like your disease is active but your doctor doesn't think so just because of your SED rate, then ask to be tested for something different (like CRP).
18 year old female
Crohn's dx in May 2009, symptoms since October 2008
Currently taking: Entocort 6mg
Off nearly all meds so the doctor can re-evaluate my diagnosis. Ugh.

Regular Member

Date Joined Jan 2010
Total Posts : 265
   Posted 4/6/2010 11:24 AM (GMT -6)   

It varies a lot.

My SED when I'm in a flare is about 15! My CRP is often low too. 

Better if you have more variation, it's easier to track your inflamation.

Male, 35 (lovely family of wife and two daughters)
Diagnosed in nov/94 - Started with Prednisone, followed by Pentasa, entocort, flagyl, Imuran, Cipro, etc.
Blockage (popcorn!!) - First Surgery 2001 (no ressection)
Severe bleedind - 2003 - Stopped by 60mg of Prednisone
Stricture leading to a ressection in Dec/2008 - Second Surgery
Now on Remicade + 100 75mg Imuran + Iron (doc said i'm in remission, but I'm not sure at all)

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Date Joined Mar 2007
Total Posts : 1016
   Posted 4/6/2010 1:36 PM (GMT -6)   
Sed rate is not a very good indicator of Crohn's activity.
CRP might be a bit better but still isn't a very accurate indicator.

For some people, neither one will elevate no matter how bad the flare.
For others, they'll elevate dramatically with even a mild flare.

They're worth looking at, but consider them only two pieces to the whole puzzle and not the final word.
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