Grapefruit Seed Extract

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farfrmnormal
Regular Member


Date Joined Oct 2009
Total Posts : 117
   Posted 4/10/2010 10:17 AM (GMT -7)   
Hi All!

I've been fighting a yeast infection since January due to a long course of Flagyl (4 months). Anyhow, I've been told I should grab some Grapefruit Seed Extract and take it orally for 14 days. I'm concerned though that it may interact with my Remicade or cause something to flare up with my Crohn's. Does anyone have any experience with Grapefruit Seed Extract? Anyone take it orally?
- Diagnosed Nov 08' but undiagnosed for 13 years prior with no major problems
- First major flare Aug-Sep 09 - I attribute it to intolerance to meds and crappy GI
- Perianal abscess - EUA with drainage and Seton put in
- Meds: Remicade for life


sr5599
Veteran Member


Date Joined Aug 2007
Total Posts : 1202
   Posted 4/10/2010 1:20 PM (GMT -7)   
Maybe you could ask a pharmacist. Grapefruit can sometime increase certain medications ... Or a doctor should know also. but, I wouldn't take it before checking with someone on your complete list of meds.
1 fistula, crohn's colitis, limited to large intestine
Compounded budesonide 3mg/daily, Cimzia, MTX . Dx Osteoporosis 10/08 started Forteo 1/27/09


spookyh
Veteran Member


Date Joined Oct 2008
Total Posts : 1342
   Posted 4/10/2010 1:54 PM (GMT -7)   
GSE is incredibly strong, so start with a low dose. The only bad effects you should experience are potential gut ache (taking with food should help), and potential die off symptoms (GSE kills off yeast and bacteria). I wouldn't think it would cause a problem with remicade or crohn's though. Are you taking probiotics? That will help get rid of yeast too.
34 years old, Crohn's disease for 15 of them
Resection of ileocecal valve on 09/22/09
Current Meds: LDN, Pentasa, Effexor XR, Zyrtec
Supplements: 3 kinds of Fish Oil, Multi-Vitamin, Vitamin D, Calcium, Magnesium, Coconut Oil, Garlic Oil, CoQ10, Enzymes
SCD since 12/01/08 - eating Stage 3 foods


farfrmnormal
Regular Member


Date Joined Oct 2009
Total Posts : 117
   Posted 4/11/2010 5:38 PM (GMT -7)   
Well.... read about it some more and decided to give it a try today. I put about 8 drops of the extract in my juice at lunch and again at dinner. Now, I am experiencing EXTREME D (The remicade pretty much stopped that) and an upset stomach. Being a crohnie though I can't always pin point what the problem is. It seems coincidental that I started feeling ill after starting it today - however, there is a flu bug going around at work too. Perhaps I should just use it once a day? I spoke with a naturopath about this product, but the pharmacist didn't know much when I asked her about it.

I'm not taking a probiotic - there are so many of them and I often had D when taking them I stopped. I do eat Activia Yogurt though that has the lacto and bifi bacteria in it.
- Diagnosed Nov 08' but undiagnosed for 13 years prior with no major problems
- First major flare Aug-Sep 09 - I attribute it to intolerance to meds and crappy GI
- Perianal abscess - EUA with drainage and Seton put in
- Meds: Remicade for life


spookyh
Veteran Member


Date Joined Oct 2008
Total Posts : 1342
   Posted 4/11/2010 6:30 PM (GMT -7)   
Eight drops is a lot, especially twice a day! You should start off with one. If that goes over okay, increase to 2, and so on and so forth. Let your body adjust. Also, you shouldn't use the same anti-fungal indefinitely, because the yeast will build up a resistance to it. You can swap GSE with things like Olive Leaf Extract, Oil of Oregano, Garlic, and Coconut Oil. There are many more, but those are the only ones I've tried so far. In the meantime, maybe try the GSE for a couple weeks and then give it a week off.

The Activia should help replenish your good bacteria some. Maybe you would do well with a single strain probiotic, like acidophillus. Start with a minimal dose, and work up. S. boulardii is supposed to be really good for killing yeast too.

Hope you recover from this setback quickly!
34 years old, Crohn's disease for 15 of them
Resection of ileocecal valve on 09/22/09
Current Meds: LDN, Pentasa, Effexor XR, Zyrtec
Supplements: 3 kinds of Fish Oil, Multi-Vitamin, Vitamin D, Calcium, Magnesium, Coconut Oil, Garlic Oil, CoQ10, Enzymes
SCD since 12/01/08 - eating Stage 3 foods


MoobyDoo
Regular Member


Date Joined Sep 2009
Total Posts : 212
   Posted 4/11/2010 7:10 PM (GMT -7)   

GSE will kill off yeast quickly. Eight drops of it sounds like a lot. 2-3 drops two or more times per day should do it. If you mix it into something strongly flavored like Welch's grape juice, you probably won't taste it much.  Diarrhea results when you have a yeast die off...not to be too too gross but a cottage cheese like result is not uncommon along with a very sour odor. 

Other things to consider to fight yeast include (along with the things mentioned by spookyhurst) biotin, monolaurin, a probiotic that is a yeast killer called THREELAC, and also aloe vera juice. I hear there is a brand of aloe vera called George's that tastes much like water. Coincidentally, I just ordered some myself today from amazon.com.  The added benefit of aloe vera is that it also has anti-inflammatory properties that can be helpful to Crohnies in addition to helping to rid the body of yeast.

 



  • MToronto2
    Regular Member


    Date Joined Apr 2010
    Total Posts : 232
       Posted 4/11/2010 8:14 PM (GMT -7)   
    Agreed on the pharmacist.

    It is always a good idea to start on the smallest amount you can with any new supplement, as a general rule. Increase slowly...
    CD 24 years. Multiple surgeries in past 10 yrs. 4 year Illeostomy. Mesh rejection. Too close to death, twice. Lare inscisional hernia. Perpetually underweight. Short bowel syndrom. Have used a variety of complementary medical therapies. Highly recommend Bowen Therapy as the best body work. Take me vites. Started Low Dose Naltrexone March 27, 2010. Got married for the only time 2008. Survive because of the love of good friends, and because I can. Happy to be alive. IBD needs more awareness and more voices willing to speak up. BE well.


    farfrmnormal
    Regular Member


    Date Joined Oct 2009
    Total Posts : 117
       Posted 4/12/2010 9:52 AM (GMT -7)   
    Thanks for the responses - I was just going by what the back of the bottle said. I think I will taper it down though and see how I tolerate it. Also, the bottle of extract I have has Oregano Oil in it as well.

    Spooky - I did some research on S. boulardi and it’s actually a yeast based bacteria that can cause Fungemia in people who are imunocompromised. Since I am on Remicade the Pharmacist actually recommended against it. I’ve been having a hard time finding probiotics that don’t cause me D – I have been taking the pearls, anyone ever use them? They’re about 25.00 for a months supply. I read that VSL is popular, but I can’t find it in Canada.

    I don't want to completely kill off the yeast; I just want to balance it properly. Will I have to start taking this for the rest of my life to prevent infections in the future?

    As I mentioned above all started because I was on the Flagyl for so long and I have always been susceptible to yeast infections when on antibiotics in the past. I’m so frustrated – I feel like I get one problem under control and another one crops up. Not to mention, when I have my surgery you can bet I’ll be on antibiotics again and may end up in this same predicament.

    Anyone else have suggestions?
    - Diagnosed Nov 08' but undiagnosed for 13 years prior with no major problems
    - First major flare Aug-Sep 09 - I attribute it to intolerance to meds and crappy GI
    - Perianal abscess - EUA with drainage and Seton put in
    - Meds: Remicade for life


    imissicecream
    Regular Member


    Date Joined Oct 2009
    Total Posts : 157
       Posted 4/12/2010 9:56 AM (GMT -7)   
    Please be sure to mention this to your doctor. Grapefruit extract can change how things are dealt with in your kidneys...especially steroids and antibiotics. So if your doctor wants to prescribe those to you, he/she needs to know you've been taking this.

    But I really hope it helps you. :)
    18 year old female
    Crohn's dx in May 2009, symptoms since October 2008
    Currently taking: Entocort 6mg
    Off nearly all meds so the doctor can re-evaluate my diagnosis. Ugh.


    farfrmnormal
    Regular Member


    Date Joined Oct 2009
    Total Posts : 117
       Posted 4/12/2010 11:19 AM (GMT -7)   
    I will advise him when I see him next week that I have been taking it.  I'm hoping I can stop taking it by then.
     
     
    - Diagnosed Nov 08' but undiagnosed for 13 years prior with no major problems
    - First major flare Aug-Sep 09 - I attribute it to intolerance to meds and crappy GI
    - Perianal abscess - EUA with drainage and Seton put in
    - Meds: Remicade for life


    MoobyDoo
    Regular Member


    Date Joined Sep 2009
    Total Posts : 212
       Posted 4/12/2010 11:50 AM (GMT -7)   
    Okay then, so my best suggestion is this:  make your own yogurt.  It is soooo good for you (if you can tolerate it) and is loaded with billions of natural healthy bacteria. Much more so than you can find with over the counter probiotic supplements. You don't have to have a yogurt maker. You can make it right in your own oven. And, I've just read a recipe for making it in a crock pot.

    farfrmnormal
    Regular Member


    Date Joined Oct 2009
    Total Posts : 117
       Posted 4/12/2010 12:08 PM (GMT -7)   
    I'd love to make my own but I am so busy right now that making it really isn't feasible. Also, I live in a basement apartment and don't have a full size fridge to house what I make.

    I think I am going to do more reading about specific types of bacteria and see what would benefit me the most.

    Off hand, how much would a yogurt maker cost?
    - Diagnosed Nov 08' but undiagnosed for 13 years prior with no major problems
    - First major flare Aug-Sep 09 - I attribute it to intolerance to meds and crappy GI
    - Perianal abscess - EUA with drainage and Seton put in
    - Meds: Remicade for life


    EMom
    Veteran Member


    Date Joined Aug 2007
    Total Posts : 990
       Posted 4/12/2010 4:36 PM (GMT -7)   
    A yogurt maker will cost you around $60.00. Most people agree that the Yogourmet brand is one of the best. You would need to purchase the freeze-dried yogurt starter, as well.

    The crockpot idea that MoobyDoo posted sounds great, too! Why didn't I think of that? idea I already own one of those!

    I would beware of Activia yogurt! skull We've had discussion threads here before on it. Most people agree that it causes D for them. shocked If you don't want to make your own yogurt, you might instead consider purchasing a high-quality organic brand like Stonyfield or another from a health-food store.
    Mom to 17 year old son diagnosed in June, 2007.
    Omega 3s, digestive enzymes, probiotics, vit. C, calcium, vit. D3, a good multivitamin and SCD legal yogurt
    Started The Maker's Diet in Sept. '07. Incorporate Specific Carbohydrate Diet (SCD) recipes, too. Med-free.

    Threads discussing diet:
    http://www.healingwell.com/community/default.aspx?f=17&m=984588
    http://www.healingwell.com/community/default.aspx?f=17&m=1533705
    http://www.healingwell.com/community/default.aspx?f=17&p=1&m=1262312


    farfrmnormal
    Regular Member


    Date Joined Oct 2009
    Total Posts : 117
       Posted 4/12/2010 6:22 PM (GMT -7)   
    EMom - thanks for your reply. I haven't had any issues with the Activia, but I have thought about purchasing something else. I am in Canada and not aware of any brands of natural yogurt I could purchase here. Anyone in Canada have some suggestions?
    - Diagnosed Nov 08' but undiagnosed for 13 years prior with no major problems
    - First major flare Aug-Sep 09 - I attribute it to intolerance to meds and crappy GI
    - Perianal abscess - EUA with drainage and Seton put in
    - Meds: Remicade for life

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