The Entocort is designed to release exactly where you need it most - the terminal ileum. If you break open the capsules, the Entocort will dissolve before it can even reach the terminal ileum...absolutely do NOT break them.
Because EC releases mainly in the TI, not only do you get help where you need it, but you also avoid many of the terrible system-wide side effects of prednisone.
Entocort can take a few weeks to reach maximum benefit - but if your Crohn's is NOT mainly in the TI it won't benefit you. Also, it doesn't work for everybody.
Give it a chance, because it is far safer than prednisone.
Daughter (22) Dx'd Crohn's 3/06. Misdiagnosed for two years, including by top pediatric Crohn's specialist as stress. No symptoms for the past three years. March '09 colonoscopy showed stricture gone but two spots of inflammation in TI. Used LDN to taper off Entocort last fall. (Was on Entocort since April 06.) Never had D. 4.5 mg LDN, SCD multivit, homemade yogurt, 5000IU vit D3, 1000 mg calcium, 27-54 mg iron, monthly B12 shots, daily oral B12 1000, 10mg zinc. SCD diet modified years ago to include potatoes and rice.