Switching from Humira to Cimzia

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SSG Mommy
New Member


Date Joined May 2010
Total Posts : 6
   Posted 5/14/2010 11:08 PM (GMT -7)   
I have perianal CD and have been on Humira since 2008. Apparently my body has or is starting to develope antibodies to it because my flares are somewhat under control but I have a couple of fistulas that will not stop draining. Anywho, my doc is switching me to Cimzia and I'm a little nervous. I was diagnosed with CD in 2005 and have been told by both my GI and Colon-Rectal surgeon that with the form I have it is a lot more unpredictable. I'm hoping this works. I was on remicade from 2006-2008 and I'm hoping this changing meds every two years isn't a common trend. I'm also on flagyl regularly as well.
 
I forgot my question ...
 
Has anyone had any adverse experiences with Cimzia? Do you like it better than Humira?
SSG Mommy
Diagnosis: Chrons Disease (2005)
Current Meds: Lialda, Humira, Nexium, Flagyl, Lomotil
 
 

Post Edited (SSG Mommy) : 5/15/2010 12:25:31 AM (GMT-6)


firecracker1
Regular Member


Date Joined Apr 2007
Total Posts : 208
   Posted 5/15/2010 9:52 AM (GMT -7)   
I was on Humira and switched to Cimzia in August 2009. I prefer Cimzia over Humira. Much less side effects and easier to give myself the injections. Two injections, once a month. Sometimes I do get a migraine the day after the injections, but it only last one day. I have also noticed that for some reason I get dehydrated easier on Cimzia. Drinking 2 liters of water a day helps with that, though.  Plus, their Cimplicity program pays my $100.00 co-pay each month. You have to reapply for it each year, but I've heard it gets approved. No additional weight gain with Cimzia at all. While on Humira I gained 40 lbs even though I eat extremely healthy and work out 4 to 5 days per week.
 
Another symptom I have had on Cimzia, but not with Humira is abscesses/boils in the groin area and on my butt. I found out, through this forum, that an antibacterial soap along with an acne wash can help keep them at bay. My dr said Flagyl and Cipro treats the boils/abscesses (which are staph infections) well, but I am unable to tolerate either of those antibiotics. 

Post Edited (firecracker1) : 5/15/2010 11:00:20 AM (GMT-6)


Aimee =)
Veteran Member


Date Joined Jun 2004
Total Posts : 1020
   Posted 5/15/2010 8:23 PM (GMT -7)   
I found them mostly interchangeable when I switched from Humira to Cimzia. The shots were administered at abt the same time frame and at home. Now, the Cimzia was a lot thicker than Humira but the Cimzia didn't burn like the Humira did.

I never had side effects on either drug.

The Cimpay plan was helpful for me - lowered my cost to $5 a box.

I think you'll find them to be fairly similar and hopefully the Cimzia will work really well for you.

SSG Mommy
New Member


Date Joined May 2010
Total Posts : 6
   Posted 5/16/2010 11:33 PM (GMT -7)   
Thanks Firecracker and Aimee for your replies. I'm on currently on Flagyl and once I start on the Cimzia it'll be reduced to twice a day verses three times a day. I have one more dose of Humira to take before I actually start on the Cimzia. My doc thought it would be best to finish out what I had then start the Cimzia on my Humira schedule. He said I'll take 4 the first time, 2 the second time, then after that one every two weeks. My fistulas have been really agressive so he said with my case one shot every two weeks will be best.
 
Are the injection sites the same? I don't do the thigh too much with my Humira, I usually do my shots in the abdomen.
SSG Mommy
Diagnosis: Chrons Disease (2005)
Current Meds: Lialda, Humira, Nexium, Flagyl, Lomotil
 
 


cleo35
Regular Member


Date Joined Feb 2007
Total Posts : 430
   Posted 5/17/2010 1:03 PM (GMT -7)   
I prefer Cimzia - I was having major muscle issues and they're much improved with Cimzia. For those of you with the Cimzia card - how long did it take for the card to get to you? It's been over two weeks - maybe I did something wrong when applying online.

ZenaWP
Veteran Member


Date Joined Aug 2007
Total Posts : 884
   Posted 5/17/2010 1:13 PM (GMT -7)   

cleo35, it took me so long to get the card I ordered online that I ended up calling and they activated a card for me over the phone right away and gave me the number so I could get my medicine filled right away.  Try calling them.  I'm not sure why it takes so long when you apply online. 

SSG, yes, you can use either your thigh or abdomen, just like on the Humira.  I've taken both and I prefer Cimzia.  It doesn't hurt as bad but it does take longer to do because it's so thick.  You have to push the syringe pretty hard, but it's a cool syringe and is comfortable to hold.  When I took Cimzia on a clinical trial, I normally got injection site whelts, but I don't get them now that I do it myself.  I also used to get upper respiratory infections a lot with both Humira and Cimzia, but the prednisone must be keeping them away right now.  So, I think you'll find the Cimzia to be very similar to Humira, but hopefully work better.    


Crohn's Disease, Acid Reflux/Gastritis, Hashimoto's Thyroiditis, Endometriosis, Arthritis, Depression/Anxiety.  Too many meds to list them all.  =) 


cleo35
Regular Member


Date Joined Feb 2007
Total Posts : 430
   Posted 5/17/2010 1:15 PM (GMT -7)   
I didn't realize the card was available until a coworker told me she got one for Humira - I've been on cimzia since Dec. so I hope that's not a problem.
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