Tysabri for Crohn's after being on Imuran? Also have Multiple Sclerosis.

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Crohns & MS
New Member


Date Joined Apr 2009
Total Posts : 15
   Posted 5/19/2010 6:58 AM (GMT -7)   
I have both Multiple Sclerosis and Crohn's disease.  I had a small bowel resection November 2009 to help me get off prednisone (which I was on for 18 months).  Since getting off prednisone I have been feeling awful!!!  I have muscle/joint pain all over.  I can't get rid of the intestinal bacteria C-Diff (3 rounds of antibiotics).  Now I am having weird throat pain. 
 
I have talked with my neruologist about Tysabri to treat both MS and Crohn's but my Gastro doctor doesn't deal with the drug because of the PML issues.  I don't know if anyone here with Crohn's has taken it?  I worry because I have been on Imuran and my understanding is that will give me a higher risk of PML. 
 
I don't know if I could deal with the PML side effect.  Especially having a wonderful husband and wonderful 3 year old daughter but I am no good to them right now anyways.
 
So wondering if anyone has done Tysabri after being on Imuran and what their doctors say about it?
 
Thanks,
Katie
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