Post Edited (njmom) : 5/23/2010 7:40:00 AM (GMT-6)
I wouldn't worry just yet. Those inflammation levels are still very low. I was told they can vary from month to month for many reasons-even sore muscles from excersise. My daughter never had inflammation levels that low even when in remission. Keep an eye on things, but I don't think those fluctuations mean much at this point.
Post Edited (BeeSting) : 5/24/2010 2:07:59 AM (GMT-6)
http://www.ecco-jccjournal.org/article/S1873-9946(08)00063-9/abstract"It is not clear whether Crohn's disease patients in clinical remission (Crohn's disease activity index<150) display normal concentrations of inflammation sensitive biomarkers. Our goal in this work was to explore the intensity of the microinflammatory response in a group of Crohn's disease patients in clinical remission...Crohn's disease patients in clinical remission displayed a statistically significant (p<0.001) elevated concentration of hs-CRP (4.83±3.8 mg/l) compared to controls (1.05±2.9 mg/l). All other bio-markers were also significantly higher in Crohn's disease patients in remission compared to controls. Similar results were obtained in a subgroup of Crohn's disease patients with very low disease activity — CDAI<75...Clinical remission is not equivalent to biochemical remission raising a question concerning the true definition of remission in Crohn's disease."
Beesting, I love how you lay out the options! Option 1 - see answer to Spookyhurst. Option 2 - this is not a flare, and if she does flare on LDN, we will kiss it goodbye - because a flare means Crohn's has been festering, all along. Option 3 - she is meeting with the doc on Wed, and will ask him what he thinks about this but this is not a flare -- instead, is a steady deterioration of biochemical markers. LDN suppressed the sed rate but it never, by itself, suppressed CRP, which has steadily risen since she went off Entocort so a one-time uptick in LDN will not fix what has been a consistent problem. Your suggestion about the starches seems to be the safest option. And we have been wondering if it makes sense to give strict SCD another try. So she started strict SCD yesterday and in 4 weeks will do another blood draw...to see whether things are getting better or worse. I read Boyle's book but was disappointed it was all about MS - didn't learn anything new. However, the video you mentioned about LDN dosage sounds fascinating.
Wish I'd gone to DDW myself, since I can't seem to get the details about Smith's findings. Paid $30 to download them from the DDW website but received an email saying I'll get them when they are ready.
Hope everybody understands that vitamin D 1,25 is NOT the vitamin D we talk about when we suggest vitamin D supplementation. The supplementation is intended to raise the other vitamin D, vitamin D 25 hydroxy.
She has also lost a lot of weight since starting LDN and can't seem to get it back on. Has been underweight since getting off Entocort in September.
Post Edited (njmom) : 5/24/2010 4:51:44 PM (GMT-6)