Studies show increased risks when taking calcium supplements/PPI's

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Becky77
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Date Joined Dec 2005
Total Posts : 1768
   Posted 8/17/2010 3:46 AM (GMT -7)   
I went to my GI a couple weeks ago, and a study had come out 2 days prior to my visit saying that people who take calcium supplements rather than making sure they get adequate calcium in their diet have an increased risk of heart attacks. My GI basically told me that if someone can intake extra calcium in their diet, it is the preferred way to get calcium.

I don't want to scare any of you, but let you all know about this because it's so recent a study. It seems that right when people start getting on board and making sure they take all the right vitamin supplements, some study comes out and makes you afraid to take vitamin supplements. So my question, after giving it some thought, is...would I rather have osteoporosis and end up an old lady with a hunchback and lots of bone pain because my bones aren't strong, or have a heart attack because I have strong bones and never broke a single one? That's my way of looking at it. What do you think?

Since seeing my GI I've tried to eat yogurt, milk, etc to get calcium rather than taking calcium chews like I was before. Maybe in a year they'll come back and say the opposite (kinda like the age old margarine vs butter that goes back and forth and back and forth on which one is better/worse for you)

Also, another study (my GI keeps up to date on studies, can you tell??) has alerted doctors who have patients on PPI's (nexium, prilosec, etc.) long term. Apparently when on these meds long term, your risk of having wrist, hip and spine fractures is increased. My dr didn't really have an opinion about this as it was only one study (I believe), however, she did try to persuade me to lower my dose of omeprazole (generic prilosec) from 40mg a day to 20mg a day. So far because of hospitalization last week I haven't been able to try. My plan was to take 40mg one day, then 20mg the next, but I get worse heartburn when taking narcotics so I haven't tried to reduce until I'm not taking lortab regularly. Obviously doctors won't just take prescriptions for PPI's away from patients because it would be cruel to withhold meds from someone with obvious reflux problems. It's more of a "oh, PPI's have been used now for some time, and we're starting to put pieces together and see that there might be other risks we didn't know about at first"

I personally think we all just need to avoid falling...that way we don't fracture things...OR like in my dreams of the future, we'll all travel around in bubbles kinda like hamster balls to prevent spreading germs and keep us safe from injury (this amuses me quite a bit to picture in my mind!) I'm rambling now, so I'll stop typing!

I would be interested to know if any of you who have seen your GI's recently have heard about these risks??
Becky

32 yr old female-dx with Crohn's in '97 after emergency resection and appendectomy, 2nd resection '05, Bilateral pulmonary emboli 10/09
Currently on Humira, Omeprazole, Effexor, Seroquel, Calcium, Vit D
Coumadin stopped 3/15/10!!!!

FunGuy
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Date Joined Oct 2009
Total Posts : 1070
   Posted 8/17/2010 5:34 AM (GMT -7)   
I am lowering my prilosec from 20mg to 10mg. I was off of it for a while but after an upper endoscopy my GI insisted I go back on it.

You have got to watch these studies as some do no put them in perspective and some don't control for variables of the study population. EXAMPLE: The reason that people that take supplemental calcium MIGHT get heart attacks COULD be that folks who take supplements don't tend to eat properly! They may be fast food eaters or very ill who don't get enough exercise. Just a thought. My second thought of the year. I think I'm over my quota! :)

Post Edited (FunGuy) : 8/17/2010 11:03:34 PM (GMT-6)


Becky77
Veteran Member


Date Joined Dec 2005
Total Posts : 1768
   Posted 8/17/2010 6:30 AM (GMT -7)   
This is exactly why I posted!!! Thanks for your response. I tend to get one track minded and can't think outside the box as to what other things might explain the studies, so it really helps to hear someone else's thoughts.

Bring on the thoughts...raise the quota to 3 a year! LOL :)
Becky

32 yr old female-dx with Crohn's in '97 after emergency resection and appendectomy, 2nd resection '05, Bilateral pulmonary emboli 10/09
Currently on Humira, Omeprazole, Effexor, Seroquel, Calcium, Vit D
Coumadin stopped 3/15/10!!!!

jpnutritionfirst
Regular Member


Date Joined Apr 2009
Total Posts : 383
   Posted 8/17/2010 6:43 AM (GMT -7)   
i just wanted to bring up the point that getting calcium through animal protein sources (milk, cheese, etc) has not been proven to prevent osteoporosis. Getting calcium sources from fruits and vegetables (which has lots of calcium btw) has been shown to prevent osteoporosis. The reason that dairy may not be good for your bones may seem counterintuitive, but it's based on the fact that animal protein represents an acid load. As a result, the kidneys excrete acid along with calcium out of the kidneys.
Crohn's diagnosed 6/08
Organic SCD since 4/09
Remicade from 6/09 to 4/10
Low-dose naltrexone since 7/5/10
Boswellia + Natren's Healthy Trinity probiotic + Cinnamon + Wild Oregano Oil + vitamin D

ZenaWP
Veteran Member


Date Joined Aug 2007
Total Posts : 884
   Posted 8/17/2010 8:34 AM (GMT -7)   
I saw a print out about this at my rheumy's office last week and it said that the increased chance of heart attack is only in patients who take calcium supplements that do not contain vitamin D as well.  They don't see the increased risk if you take vitamin D supplements, so make sure your calcium also has vitamin D in it...the ones I take do. 

Crohn's Disease with Arthritis, Non-Erosive Reflux Disease, Gastritis, Hashimoto's Thyroiditis, Endometriosis, Depression/Anxiety 

njmom
Veteran Member


Date Joined Apr 2006
Total Posts : 1884
   Posted 8/17/2010 8:54 AM (GMT -7)   
jpnutritionfirst, I would appreciate it if you could provide a link(s) to the evidence for what you are saying.
 
Here is a link to the article about calcium supplements and heart attacks:
 
 
Here is a link to the study:
 
 
Two things to consider - a) the effects of calcium supplements on people with Crohn's versus the effects on the rest of the population has not been studied, so we don't know whether the results apply to Crohn's patients and b) as the article states, these supplements did not include vitamin D mixed with calcium. This means it is possible that vit D mixed w/calcium might be OK,  but has not been studied. 
 
Also, I noticed most of the study participants had high levels of vitamin D 25 hydroxy - unlike many Crohn's patients, who  are vitamin D deficient. 
 
This study is interesting, but does not offer any clear path for calcium treatment for Crohn's patients. 

Becky77
Veteran Member


Date Joined Dec 2005
Total Posts : 1768
   Posted 8/17/2010 9:10 AM (GMT -7)   
Actually, I should have provided links, and I apologize for not doing that.

I will be seeing my endocrinologist soon and will ask him his opinion on what I, as a CD patient with osteopenia and vitamin D deficiency should be doing. I'll let you know what he thinks.

Out of curiosity, jpnutritionfirst are you a nutritionist, or do you work in a medical field, or do you just research a lot on your own?
Becky

32 yr old female-dx with Crohn's in '97 after emergency resection and appendectomy, 2nd resection '05, Bilateral pulmonary emboli 10/09
Currently on Humira, Omeprazole, Effexor, Seroquel, Calcium, Vit D
Coumadin stopped 3/15/10!!!!

kazbern
Veteran Member


Date Joined May 2010
Total Posts : 8375
   Posted 8/17/2010 10:18 AM (GMT -7)   
If the trade on PPIs is esophageal cancer vs. hip fracture, I'm going for the hip fracture.  DO NOT want esophageal cancer.

tewcute
Regular Member


Date Joined Mar 2010
Total Posts : 300
   Posted 8/17/2010 11:47 AM (GMT -7)   
I talked to the pa at the drs office about as I was there today for followup. She said there was not enough evidence with this study for her to tell me to come off of the supplements. Mine is with Vitamin D and I have been on full dose of Entocort since May so there is worry about osteoporosis. Another good tip for people who are concerned is if you are strong enough do weight bearing exercises. I weight train twice a week now and have read that it is great for your bones.
Dx with crohns February 25, 2010. But suspect I had it since 2002 with very mild symptoms.
4 lialda a day.
3 entocort daily for the next few months
hyosamine for daytime
Bentyl for evening
Multigen

jpnutritionfirst
Regular Member


Date Joined Apr 2009
Total Posts : 383
   Posted 8/17/2010 1:49 PM (GMT -7)   
Hi, regarding how milk does not prevent osteoporosis, I've read it from multiple sources. One i remember in particular is The China Study by T. Colin Campbell. Check out this website for a good summary of this issue(don't be put off by the website title). http://www.milksucks.com/osteo.asp I do admit that it is still a controversial topic. I should have said that upfront.

Monkiray, yeah I'm in the medical field. I've discussed this issue with many nephrologists and even they don't have a consensus about it. They do agree, however, that animal protein (and thus milk) does cause you to urinate more calcium. The data is also clear that drinking milk does not prevent osteoporosis. Eating more fruits/vegetables does have a protective effect.
 
 
 
20. Do not use the forum to give professional medical advice. If you are a medical professional, please remember the forums and chat are for patient support and not to be used for distributing professional medical advice and/or using the forum to represent your professional services.
 
 
JP you have not broken any rules yet, but I am posting this rule so that others don't cause you to break forum rules, by asking medical advice etc:)

Post Edited By Moderator (Nanners) : 8/21/2010 8:43:23 AM (GMT-6)


spookyh
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Date Joined Oct 2008
Total Posts : 1342
   Posted 8/17/2010 4:23 PM (GMT -7)   
I've read A LOT of stuff that debunks the China Study . See a good analysis at http://www.proteinpower.com/drmike/cancer/the-china-study-vs-the-china-study/ . Also, http://rawfoodsos.com/2010/07/07/the-china-study-fact-or-fallac/ . For "The China Study Smackdown Roundup", go to http://freetheanimal.com/2010/07/the-china-study-smackdown-roundup.html .

EDIT: Summary of the analysis at rawfoodssos.com:

"In sum, “The China Study” is a compelling collection of carefully chosen data. Unfortunately for both health seekers and the scientific community, Campbell appears to exclude relevant information when it indicts plant foods as causative of disease, or when it shows potential benefits for animal products. This presents readers with a strongly misleading interpretation of the original China Study data, as well as a slanted perspective of nutritional research from other arenas (including some that Campbell himself conducted)."
35 years old, Crohn's disease for 15 of them
Resection of ileocecal valve on 09/22/09
Current Meds: LDN, Pentasa, Effexor XR
Supplements: 3 kinds of Fish Oil, Multi-Vitamin, Vitamin D, Calcium, CoQ10, Enzymes
SCD since 12/01/08 - eating Stage 3 foods

Post Edited (spookyhurst) : 8/17/2010 5:30:25 PM (GMT-6)


jpnutritionfirst
Regular Member


Date Joined Apr 2009
Total Posts : 383
   Posted 8/17/2010 6:18 PM (GMT -7)   
you can't debunk the fact that milk doesn't prevent osteoporosis, it comes from the nurse's health study
Crohn's diagnosed 6/08
Organic SCD since 4/09
Remicade from 6/09 to 4/10
Low-dose naltrexone since 7/5/10
Boswellia + Natren's Healthy Trinity probiotic + Cinnamon + Wild Oregano Oil + vitamin D

jeanneac
Veteran Member


Date Joined Feb 2009
Total Posts : 1812
   Posted 8/17/2010 6:38 PM (GMT -7)   
well, for post menopausal women, you can take all the calcium you want and still get osteoporosis. It's the lack of estrogen that keeps us from utilizing the calcium from what I've been told.
d 1/09 with colitis sigmoid colon with some diverticular disease as well
IBS, high BP, fibromyalgia, Mixed Connective Tissue Disease
claritin, diovan, progesterone, VSL#3 probiotic, Vit. D, colazal, omeprazole for reflux.
Blood test positive for Crohn's via prometheus ibd serology panel ASCA
Positive ANA.
Currently on flagyl and it is helping. Have apt with surgeon soon

spookyh
Veteran Member


Date Joined Oct 2008
Total Posts : 1342
   Posted 8/20/2010 10:47 PM (GMT -7)   
I just came across something saying only raw milk is good for your bones: http://www.cheeseslave.com/2009/04/14/got-osteoporosis-drink-raw-milk/
35 years old, Crohn's disease for 15 of them
Resection of ileocecal valve on 09/22/09
Current Meds: LDN, Pentasa, Effexor XR
Supplements: 3 kinds of Fish Oil, Multi-Vitamin, Vitamin D, Calcium, CoQ10, Enzymes
SCD since 12/01/08 - eating Stage 3 foods
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