gingerjem, welcome! I also have acid reflux (although mine was called NERD last time I had an upper GI - Non Erosive Reflux Disease) and hypothryoidism (Hashimoto's). I am one of those people kazbern mentioned who have to switch up their ppi's every year or so because they stop working. It also has helped me to elevate the head of my bed using 2x4s. I'm also in the process of being scheduled for enteroclysis, which I don't think I've had before. We are doing that and then another colonoscopy and upper GI, as my GI now wants to "make sure" I have Crohn's, 5 yrs after being diagnosed (and it took them 8 yrs to diagnose me). I also have Crohn's-related arthritis (which really doesn't make sense if I don't have Crohn's!). My rheumy is also my favorite doctor. But, I can tell you that it can be very difficult to treat the arthritis without aggrevating the Crohn's...so many of the arthritis meds hurt my stomach and so many of them can cause stomach pain, diahrrea, etc. I hope all of your tests go well and that the rheumy rules out RA.