Vitamin D 50,000 IU Weekly - side effect?

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EruditePaul
Regular Member


Date Joined Jan 2006
Total Posts : 254
   Posted 6/30/2011 6:09 PM (GMT -7)   
My G.I. doctor called me today and said my Vitamin D level from blood test is low (17, normal is 30). He prescribed me 50,000 IU of Vitamin D once per week for 8 weeks. Has anyone here taken Vitamin D before? Any side effect from this medicine?

Thanks

Paul

IamCurious
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Date Joined Jan 2010
Total Posts : 2355
   Posted 6/30/2011 7:21 PM (GMT -7)   
Congratulations for having a GI who is progressive enough to test your blood levels of vitamin D. Most people here find vitamin D crucial for maintaining health not only for Crohn's but arthritis, fibromyalgia, depression, etc. Here is one of many threads discussing vitamin D here on the Crohn's forum.

Most people do not have any side effects, but the last post on this thread discusses a possible work-around in the rare case that the 50,000 IU pill the doctor gave you causes a stomach upset:

www.healingwell.com/community/default.aspx?f=17&m=2132353
Male/59 DX ulcerative colitis Feb08, possible Crohn's colitis DX Mar10.
No Meds, allergic to Mesalamine. Remission since Mar10. Psyllium seed mixed with VSL3 especially helpful. Food journal instead of SCD.

Multivitamin, extra D3, K2, high gamma E, probiotics, fish oil, glutamine, magnesium, phos choline, resveratrol, S. Boulardii, boswellia, curcumin. Watch gluten, lots of fruit & vegetables (but no plums or kale), no soda, no HFCS, no trans fat, tea instead of coffee, no shellfish, few processed foods, no carrageenan.
Nature created all of the locks, therefore Nature has all of the keys

pmedic
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Date Joined Nov 2009
Total Posts : 1482
   Posted 6/30/2011 9:22 PM (GMT -7)   
I was on it recently and was unable to take 50,000 all at once. Instead, I used the 2000 unit capsules of d3 and took 7,000 units per day. I felt so much better when I was on it. I am thinking I am low again and welcome the high dose d3! 

lamb61
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Date Joined Jan 2005
Total Posts : 1567
   Posted 7/1/2011 4:23 AM (GMT -7)   
DH did this last year as he has hyperparathyroidism. No noticable side effects that we knew of, the endo didn't warn or any either. My GI test noted mine were a little low and prescribed Caltrate with Vit D.

CrohnieToo
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Date Joined May 2003
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   Posted 7/1/2011 4:51 AM (GMT -7)   
I was started on 100,000 IU vitamin D weekly by my endocrinlogist about 2003 or so and was on that dose for maybe 3 years. Then it was dropped to 50,000 IU weekly and a year or so ago we were able to drop the dosage to 50,000 IU every other week which is the dosage I am on now. I sure have never had any side effects that I am aware of.
My computer says I need to upgrade my brain to be compatible with its new software.

EruditePaul
Regular Member


Date Joined Jan 2006
Total Posts : 254
   Posted 7/1/2011 6:27 PM (GMT -7)   
It has been 24 hours since I took the first pill of Vitamin D 50,000 IU. I have not noticed any side effect as yet. Next pill is 6 days away.

mdf34
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Date Joined Feb 2010
Total Posts : 925
   Posted 7/2/2011 2:54 PM (GMT -7)   
My belly area would feel a bit rough hours after taking it, but once I quit taking magnesium, it just staying feeling a bit rough, nothing came of it except a tiny bit of discomfort.(small)
Diagnosed (FINALLY) UC Sept 09/Diagnosis amended 5-3-10 to Crohn's
Osteopenia DX July 2010
Taking Pentasa 500mg/8x/day
Entocort 3X/day
Bentyl as needed
1000 mg Vitamin C
Prilosec 1X/day
Flonase
Caltrate-D 1000mg/day

Zanne
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Date Joined Apr 2005
Total Posts : 3763
   Posted 7/2/2011 3:13 PM (GMT -7)   
I have been taking 50,000 IU 1X week for years, then a few years ago, my D was still too low and my Endocrinologist told me to take some daily in addition, so I now take either 5000 IU or 10,000 IU daily depending on what I can find on sale. I don't have any side effects. My D level is still low, but it is slightly higher than it was before the huge increase.

ivy6
Elite Member


Date Joined Sep 2005
Total Posts : 10404
   Posted 7/4/2011 5:21 PM (GMT -7)   
My pharmacist says you're better off taking it with a spoonful or two of something fatty, like ice cream or yoghurt, to avoid getting an upset stomach.
Co-Moderator Crohn's Forum.

Medications for Crohn's ~~ Diet and Nutritional Therapy for Crohn's ~~ Dealing with Abscesses and Fistulae ~~

hottamale
New Member


Date Joined Mar 2011
Total Posts : 15
   Posted 7/5/2011 12:03 PM (GMT -7)   
I've been put on it many, many times. I am constantly deficient. I've never had any side effects from it. You can check for side effects on this website:

www.medlineplus.org

Catch 22
New Member


Date Joined Jul 2011
Total Posts : 4
   Posted 7/9/2011 8:51 PM (GMT -7)   
Used to be, back in the day, they'd give children 250,000 IU of vitamin D; it would last a year. It's a fat-soluble vitamin, so it's stored and released slowly. 50,000 IU/week is pretty good; I take 5,000 IU/day (the "NOW" brand stuff). The effect is not immediate by any means; it is cumulative and, particularly for those that are deficient, it will take a long time to normalize- probably weeks, months. It's a slow fix, but a good one. Note that the highest no observable effects level is about 10,000 IU/day for healthy individuals; it is difficult to determine how much higher it would be for Crohnies, or others that suffer from diarrhea.

While the discussion on the "hygiene hypothesis" has revolved around germs and worms, it is interesting to note that the developing countries in which Crohn's (and other autoimmune diseases) are so rare are also very sunny; in fact, the development of heavily pigmented skin is a form of protection against hypervitaminosis D, which causes joint pain and other problems. From this, it is conceivable that insufficient vitamin D is a contributing cause to Crohn's disease; we know this is probably the case with multiple sclerosis, as the incidence of the disease increases with the northern latitudes.

totallyforgiven
New Member


Date Joined Dec 2012
Total Posts : 3
   Posted 3/22/2013 7:37 PM (GMT -7)   
I have been on the 50,000 Vitamin D for 2 years now and have not had any side effects. I also take Diovan - 320 mg, a day, lopressor 25 mg 2 times a day, Lovaza 2000 mg - 2 times a day, Welchol 625 mg, 3 pills 2 times a day, low-dose aspirin 1 a day.

I have an Ascending Aortic Aneurysm (4.05 cm) and 2 leaky heart valves. I am 51 years old. My cardiologist told me not to worry, but it is hard not too, have thought about getting a second opinion, but not sure if I should. I have trouble with my blood pressure dropping and gets really low, makes it hard to do my job.

stereofidelic89
Veteran Member


Date Joined Sep 2011
Total Posts : 1928
   Posted 3/23/2013 9:41 PM (GMT -7)   
50,000 IU of Vitamin D?! Although I support the growing research of Vit. D's benefit to cardiovascular disease, I have to ask -- what are these doctors thinking when they prescribe such an insane amount?!
male, Diagnosed Crohns-Colitis Sept 2011
Gluten Free-Limit Grains+Sugar, VSL#3, Slippery Elm, Suppositories #2, Asacol, Digestive Enzymes
Metametrix Labs stool testing reveal yeast overgrowth, parasite, h.pylori

STEVE55
New Member


Date Joined Jun 2012
Total Posts : 9
   Posted 3/24/2013 12:40 PM (GMT -7)   
It doesn't seem like a good idea at all. See the following two articles which discuss possible negative outcomes from such a high dose. There is no reason to do such a high dose in my opinion. Yes, your low. so supplement with a normal dose and reassess where you are in a month or two.
 
 

CrohnieToo
Veteran Member


Date Joined May 2003
Total Posts : 9448
   Posted 3/25/2013 12:27 AM (GMT -7)   
All the while I've been on high dose vitamin D we've run regular blood draws to ensure that I do maintain an acceptable level of vitamin D w/o deficiency nor overdosing.
Crohn's symptoms began mid-1975; Dx'd at Mayo Clinic, Rochester, early 1976; resection of 18" mid-ileum early 1978; 20 year total remission; symptomatic remission 1998 to current.

My computer says I need to upgrade my brain to be compatible with its new software.

randynoguts
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Date Joined Jan 2003
Total Posts : 5963
   Posted 3/25/2013 1:47 AM (GMT -7)   
ha got ya all beat! from all my testing with my short bowel. I do not absorb nearly enough.. I was on 50k 3 times a week but it still would not go up. since ive been out of the hospital in dec, they have me on 50k every day... with little improvement... ;o) no side effect that I can noticeand yes my blood work is checked weekly etc...

NiceCupOfTea
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Date Joined Jan 2010
Total Posts : 6042
   Posted 3/25/2013 6:34 AM (GMT -7)   
I asked my GP about testing my Vitamin D levels and he said that people aren't normally low in Vitamin D. I didn't argue about it, but it did leave me wondering why every person and his or her dog on HW takes Vitamin D supplements :-/

stereofidelic89
Veteran Member


Date Joined Sep 2011
Total Posts : 1928
   Posted 3/25/2013 1:44 PM (GMT -7)   
randynoguts said...
ha got ya all beat! from all my testing with my short bowel. I do not absorb nearly enough.. I was on 50k 3 times a week but it still would not go up. since ive been out of the hospital in dec, they have me on 50k every day... with little improvement... ;o) no side effect that I can noticeand yes my blood work is checked weekly etc...


Randy, did they ever look into the reason why you are not absorbing vitamin D? Some vitamin deficiencies are caused by a multitude of things, and some vitamins or minerals in the body cannot be absorbed without the accommodation of other vitamins. Take Calcium and Vitamin D for example, one depends on the other.

Still, your best bet for absorption of vitamin D may be through natural sunlight.

randynoguts
Veteran Member


Date Joined Jan 2003
Total Posts : 5963
   Posted 3/26/2013 3:04 AM (GMT -7)   
I only have about 2 ft of intestine.... so I don't absorb much of anything.. have been on IV feeding for over 13 years..

Somedude
Veteran Member


Date Joined Jul 2011
Total Posts : 3393
   Posted 3/26/2013 10:44 AM (GMT -7)   
WAT?! a vit d pill of 50,000 iU....***bbq, I wanna see that
DX Ulcerative Colitis (pancolitis) - May 2011. (Remicade Max/6 wks, LDN, SCD, vitam.)

"Life is like a box of chocolates; you never know what you' gonna get. " by Forrest Gump

randynoguts
Veteran Member


Date Joined Jan 2003
Total Posts : 5963
   Posted 3/26/2013 6:24 PM (GMT -7)   
green gel pill about a little more than a 1/2 inch long..

dinkley
Regular Member


Date Joined Feb 2010
Total Posts : 108
   Posted 3/27/2013 6:04 AM (GMT -7)   
Found on line: http://www.amazon.com/Bio-Tech-D3-50-000-100-Caps/dp/B000A0F2B2, and elsewhere.

ideasputtowork
New Member


Date Joined Jun 2014
Total Posts : 1
   Posted 6/10/2014 4:06 PM (GMT -7)   
It's much cheaper and safer to buy the over-the-counter Vitamin D3 pills that you take daily. The prescription strength pills have no advantage over the smaller ones, and have lots of side effects. If you are prone to asthma, the 50,000 IU pills can precipitate a severe asthma attack. Also, compliance is much better with a daily pill than it is with one that you must remember once each week.

beave
Veteran Member


Date Joined Mar 2007
Total Posts : 647
   Posted 6/11/2014 3:05 PM (GMT -7)   
ideasputtowork said...
It's much cheaper and safer to buy the over-the-counter Vitamin D3 pills that you take daily.


Two months' worth of my prescription 50,000iu pills cost $8. That's about as cheap, if not cheaper, than similar OTC vitamin D pills.

ideasputtowork said...
The prescription strength pills have no advantage over the smaller ones, and have lots of side effects. If you are prone to asthma, the 50,000 IU pills can precipitate a severe asthma attack.


Link?

ideasputtowork said...
Also, compliance is much better with a daily pill than it is with one that you must remember once each week.


How is it easier to remember something every day than to remember it once a week?

Nazareth
New Member


Date Joined Jun 2014
Total Posts : 5
   Posted 6/14/2014 10:11 PM (GMT -7)   
I dunno about 50,000 iu of D causing asthma attacks, but vitamin D has been suggested for Asthma as it has anti inflammatory action and blocking the cascade of inflammation-causing proteins in the lung-

http://www.webmd.com/asthma/news/20100910/vitamin-d-may-improve-asthma-control

curious as to why someone stopped taking magnesium and Vitamin D together? Was it because of Diarrhea? If so you can make a magnesium rub by melting magnesium chloride flakes (get them from Amazon of health food stores) in hot water- put in a spray bottle, and rub about 10 sprays into skin- Magnesium is well absorbed through the skin and won't cause diarrhea that way or stomach upset- Magnesium is an important mineral for pain in muscles and is usually deficient in crohn's patients and m uch needed usually-
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