I saw my GI last week. he was mentioning thath he doubts entyvio will do much for me and started the discussion on stellara. My gi works with a group that is one of the medicine research facilities in the USA so he is very familiar with these medications and how effective they ae for each situation.
during the discussion, he mentioned that all the testing so far has centered on symptom relief/improvement. but no studies about mucous healing-i.e. reduction /elimination of ulcerations and such in the small bowel. So, patients like me have no real data to guide the doctors. But he said they are now looking to start adding requirement of a colonoscopy before and then at certain time frames to see the internal improvements of a medication. today, while some scopes are done with trials, he said there is no set test parameters as the focus has been to help a patient feel better. but now they are going further.
for patients like me who are now being classified as "drug resistant", this might be good news for future medications and as he stated will help with costs as the doctors can focus on specific drugs for each patient, not just roll through them. hoping this happens soon!
as far as entyvio and me, he stated that their research showed that while moving the drug fro every 8 weeks to every 6 does help a few more patients, patients that don't exhibit a lot of symptoms, they saw no change in the mucous ulcerations. thus, why he thinks I will be moving on from it.
just wanted to share