Crohn's disease successfully treated with the paleolithic ketogenic diet N=1

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Old Mike
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Date Joined Jan 2007
Total Posts : 3774
   Posted 10/8/2017 8:13 AM (GMT -6)   
I usually hang out in the UC forum,but thought you should see this here.
Was it the ketosis or elimination of just about everything except meat.
No meds helped this kid.
Old Mike

www.ijcasereportsandimages.com/archive/2016/009-2016-ijcri/CR-10690-09-2016-toth/ijcri-1069009201690-toth-full-text.php

eleanor_rigby
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Date Joined Sep 2016
Total Posts : 33
   Posted 10/8/2017 8:17 AM (GMT -6)   
journals.lww.com/jpgn/Abstract/2017/09000/Lack_of_Mucosal_Healing_From_Modified_Specific.10.aspx

said...
Seven subjects were identified, all on the specific carbohydrate diet or modified specific carbohydrate diet..... Complete macroscopic mucosal healing of both the ileocolon and upper gastrointestinal tract was not seen in any patient.

Post Edited (eleanor_rigby) : 10/8/2017 8:20:44 AM (GMT-6)


NiceCupOfTea
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Date Joined Jan 2010
Total Posts : 9930
   Posted 10/8/2017 6:14 PM (GMT -6)   
eleanor_rigby said...
journals.lww.com/jpgn/Abstract/2017/09000/Lack_of_Mucosal_Healing_From_Modified_Specific.10.aspx

said...
Seven subjects were identified, all on the specific carbohydrate diet or modified specific carbohydrate diet..... Complete macroscopic mucosal healing of both the ileocolon and upper gastrointestinal tract was not seen in any patient.


Thank you for this link. While 7 patients is a tiny sample, it's interesting to see that that the SCD doesn't have miraculous healing powers after all.

@Mike - I read your link as well.

Not remotely convinced by the paleo cake causing the boy's terminal ileum to thicken. That just sounds like something they made up in retrospect to explain the results seen on the ultrasound.

Anyway, the diet is even more restrictive and unpalatable than the SCD. Not my cup of tea and can't see it helping most people with Crohn's.

Canada Mark
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Date Joined Jan 2013
Total Posts : 3479
   Posted 10/8/2017 8:00 PM (GMT -6)   
Hi Mike,

Thanks or sharing. That is interesting. A thought occurred to me though as an alternative to Ketosis or the meat only.

I wonder if the same boy would have had equal effect going to a liquid elemental only diet. Same thing really, except the elemental diet proteins are broken down into amino acids.

I think both diets would be better called low antigenic diets.
Diagnosed Crohns-Colitis 12-13 years ago - Past Meds: Antibiotics, Prednisone, Methotrexate, Imuran, Remicade - Current Meds: Imuran 150mg/daily, Natural: WOO/Thyme Oil, All organic food no additives as best as possible. I stopped taking probiotics as I felt they were not helping much.

“The only person you're destined to become, is the person you decide to be"

Old Mike
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Date Joined Jan 2007
Total Posts : 3774
   Posted 10/9/2017 4:32 AM (GMT -6)   
Hey Mark: They tried formula feeding. I have been doing a lot of research on ketones, they for sure block the
NLRP3 inflamasone, another big effect is they block lactate dehydrogenase,they also inhibit histone deacetylase.
You can do all of this with ketone supplements, I believe so perhaps no need to be over restrictive with a ketogenic diet. Histone deacetylase can inhibit NfKb, so you can see where I am going with this.
Old Mike
The condition of the patient further deteriorated and therefore on 07 November 2014 exclusive formula feeding was initiated. At this time mesalazine, multivitamin, vitamin D3 and calcium were discontinued. Pantoprazole was discontinued within two weeks. Formula-based nutrition resulted in the resolution of abdominal pain but other symptoms persisted

Post Edited (Old Mike) : 10/9/2017 5:14:54 AM (GMT-6)

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