The Prometheus IBD Serology 7 test looks for serum markers that are found in those with inflammatory bowel disease [IBD]. Here are some statistics:
Sensitivity - The likelihood of a positive test result among those who do have the disease:
IBD = 93%
CD = 88%
UC = 93%
Positive Predictive Value - The probability that a positive test result is correct:
IBD = 96%
CD = 96%
UC = 89%
So, yes one can have a positive test result and NOT have the disease. But, the majority that have a positive result do have the disease. I am not familiar with you and don't know what tests you have had. Some questions: Did you have a colonoscopy and did they take biopsies during the scope? Have you had a capsule endoscopy? If the disease in present in the small bowel, it does not always show up on xrays or CT scans. I hope this information has helped.
I had a positive Prometheus test for CD, capsule endoscopy that showed edema and 'red splotches' in my jujenum that was indicitive of CD, colonoscopy that showed swelling and ulcerations indicitive of CD, and biopsies that came back positive for colitis/CD....but since I had a clear scope with biopsies last month, my GI now wonders if I ever really had CD...
I'm sticking with the CD dx.
In His Grip
AlwaysRosie "We can't control the waves, but we can learn how to surf!!"
Co-Moderator - Lupus Forum
UCTD, Inflammatory Arthritis, Diverticulosis, (recent dx - Sjogrens, Crohn’s 4/08)
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The serology 7 test is pretty darn accurate if you have Crohn's. I was first diagnosed through the capsule study, but have never yet had a positive diagnosis through biopsy. This is really common because sometimes people only have active disease where the scope can not reach. On the original Promethius Test, I came back as a negative.(Many years ago), but when the Serology 7 Test came out, I came back with a extremely positive rating 2 times. I still have had many recent scopes that have come back as clean with some inflammation, but the Serology 7 results have come back the same to 2 different G.I.'s.
This a minor pet peave of mine, but everyone Crohn's Disease is not spelled Chrons or Chron's. I am not trying to hurt feelings, but we have got to learn everything we can about this wonderful disease that we have.