Update on Imuran

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laura l
Regular Member

Date Joined Oct 2006
Total Posts : 94
   Posted 9/16/2007 9:03 PM (GMT -6)   
Hello....first of all i would like to thank all of you's who posted replies to my concerns on beginning imuran on Sept 4th. well...as i promised here is the update-to make a long story short, the discomfort, and severe hurting in my upper-mid stomach got even worse after the third day of being on the imuran. it seemed to get worse at night and two nights for sure i wanted to go to emergency and be pumped with morphine so badly!! i went to my specialist on the 12th and he said to hang in there till the 1st set of blood work came back to see if anything came back abnormal. go figure....the blood work came back normal (but then again i was only on it for a week) and i told the nurse about my stomach and she said to take a break for a couple of days to rest my stomach and then start up again. it has been three days since not taking it and my stomach felt normal again. normally i would take it in the am as i was told to but tonight i have taken my first dose (100mg) after three days. i am dreading this all over again from the bad experience i had last week and i am hoping and praying that taking it at nice is the answer and my stomach wont be hurting horribly like it was for the 10 days. i know from alot of your experiences you said you took it at night and you were fine on it but see...the difference here is i wasnt nauses or anything, during the day my stomach hurt badly (no pain, just hurt) and of course loss of appetite big time!! but it was usually at night when i was running to the bathroom, and stomach hurt like a bugger, a HUGE OWIE!! i am scared AGAIN because i am so scared of the hurting and also because if my body rejects this drug i am scared of not knowing what will be the next solution. i am trying so hard to think positive but with the first bad experience last week its kind of hard to stay positive and hang in there. thanks to all who have given me their opinions and their support on my experience with imuran and i am asking you to keep your fingers crossed for me. "thanks" 
Laura lee-diagnosed with crohns-1986/1st surgery-1998 small bowel resection,(removed part of illeum/appendix) 8yrs of remission-Oct'06 diagnosed with crohns being back! 

Veteran Member

Date Joined Feb 2004
Total Posts : 6518
   Posted 9/16/2007 10:31 PM (GMT -6)   
sorry you are having this trouble LL. Are you tsking the imuran with food? If not, try to take it with breakfast or lunch and not at night. Your stomach can sometimes stop working at night and what ever is in it just sits. Not a good place for a strong med. Also remeber it will take a month or so to get the levels correct in your body. Doc may change your dosage. If for some reason you can not take it, not to worry, there are other things your doc can try. We are all different so what works for one may not work for all. Good lucck and keep us posted.
If we would read the secret history of our enemies,we would find in each mans life sorrow and suffering enough to disarm all hostility.

Veteran Member

Date Joined Oct 2004
Total Posts : 3042
   Posted 9/17/2007 6:00 AM (GMT -6)   
Hi Laura lee, I agree with sniper. I am on Imuran 150 mg. I take it after breakfast. I have been
on Imuran for over 2 years with no problems. Make sure when you take the Imuran take with a full
glass of water. Don't take on an empty stomach.
Hi, I am teddybearweiser, I am a male.
I was diagnosed with crohns disease when i was admitted to the hospital
in 1992, in Jan of 1993 I was back in the hospital for surgery for my crohns. I had part of my right colon resectioned with ilecolonstomy.
 My GI doctor has me on Asacol, Dicyclomine,Imuran,Celebrex and Remicade. B-12 injection once a month.
My Internest doctor has me on Lisnopril-HTCZ and Folic Acid. Diagnosed
with Osteoarthritis July 2007

Veteran Member

Date Joined Mar 2007
Total Posts : 4527
   Posted 9/17/2007 7:08 AM (GMT -6)   
Hi The only thing you can do is try and see where it goes hopefully you atr something that didn't agree or you just were having a flare. Like sniper said there are other things available so don't be nervous. Glad you had some relief maybe they are kicking in. lol gail

Elite Member

Date Joined Apr 2005
Total Posts : 14995
   Posted 9/17/2007 8:41 AM (GMT -6)   
Another option is 6mp. Yes same drug family, it just processes a little differently in your system. I had some problems with Imuran upsetting my stomach, but tried the 6mp (at night) and had no problems. I no longer take either one, but just wanted to let you know I had less side effects with the 6mp. Good Luck!
Been living with Crohn's Disease for 32 years.  Currently on Asacol, Prilosec 60 mg, Estrace, Prinivil, Diltiazem, Percoset prn for pain and Calcium.  Resections in 2002 and 2005.  Recently diagnosed with Fibromyalgia and doing tests to see if I have Inflammatory Arthritis or AS.

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