Hi Dragonfly -
After his loading dose of 4 shots he was very, very fatigued and nauseated. Those symptoms started about 2 hours after the shots.
The second round he again had intense fatigue but also had a more general malaise, bad belly pain, bad headache, nausea. He "looked" sick if you know what I mean - pale and sweaty and could hardly walk from fatigue. That hit him within an hour of the shots.
The third round he was fatigued for a day or so but nothing else and the fatigue set in about an hour after the shot.
This time was more like the second round but with the intensity turned down. He started feeling bad about 90 minutes after the shot.