switch to methotrexate from 6-mp

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Veteran Member

Date Joined Sep 2006
Total Posts : 845
   Posted 10/31/2007 3:23 PM (GMT -6)   
I have been on 6-mp and remicade for a long time now, but my Rheumy wants to switch me from 6mp to methotrexate injections.  This makes me a little nervous because of all of the posts that I have read on here about methotrexate and the side effects.  I was also told that this will help the remicade perform better.  This would be awsome because I am already at the max dosage 10 every 4 weeks and it is only lasting about 2 weeks now.  It has been a great drug for the past 3 years, but I am building up antibodies.  I tried Humira and got really sick and had to go back to Remicade. 
I would love to hear from anyone that has had good or bad reactions from this.  I have also read about the birth defects that can come from this medication and would like to hear from anyone that had a child on this medication.  My wife and I would eventually like to have children and want to make sure that this will not stop us when I go off of the medication for this purpose.
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