Remicade is made up of a protein. The body can suddenly decide that this protein is a "foreign" substance and that it must attack. To do that, the body produces antibodies to fight the foreign protein. These antibodies can then produce their own set of symptoms. Don't worry that this will happen to you. There are many people that have been on Remicade longer than you without building antibodies.
In my unscientific opinion, those that are builders of antibodies seem to have other autoimmune issues/diseases or have other complicated histories or conditions. Just my observation from reading a lot of posts here. Hopefully, Remicade will continue to do its magic for you for a long, long time.
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CD, Ankylosing Spondylitis, small fiber peripheral neuropathy, avascular necrosis, diffuse connective tissue disease, Sjogren's Syndrome ?