please exlain this anti body thing!!!!

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apples
New Member


Date Joined Oct 2007
Total Posts : 9
   Posted 10/31/2007 7:40 PM (GMT -7)   
from reading several posts, i am learning that you can build up antibodies after being on remicade for a long period of time. this is news to me...my gi never discusses the down side to remicade.  can someone please explain this to me.... i have been on remicade for 4 years and am doing great....
Applesl
 
30 year old female ~ Mom of 6 month old Jack
Diagonosed with Crohns in Dec. 2003
Previous meds - Asacol, Pentasa, Prednisone, 6MP
Current meds - Remicade ONLY(every 10 weeks)
  • I have been on Remicade for almost 4 years!!!
  • Received Remicade throughout pregnancy
  • Currently breastfeeding!
 
 
 


Ides
Forum Moderator


Date Joined Nov 2003
Total Posts : 7077
   Posted 10/31/2007 8:48 PM (GMT -7)   
Remicade is made up of a protein. The body can suddenly decide that this protein is a "foreign" substance and that it must attack. To do that, the body produces antibodies to fight the foreign protein. These antibodies can then produce their own set of symptoms. Don't worry that this will happen to you. There are many people that have been on Remicade longer than you without building antibodies.

In my unscientific opinion, those that are builders of antibodies seem to have other autoimmune issues/diseases or have other complicated histories or conditions. Just my observation from reading a lot of posts here. Hopefully, Remicade will continue to do its magic for you for a long, long time.
Moderator Crohn's Disease Forum
CD, Ankylosing Spondylitis, small fiber peripheral neuropathy, avascular necrosis, diffuse connective tissue disease, Sjogren's Syndrome ?
 


thenay
Regular Member


Date Joined May 2006
Total Posts : 167
   Posted 10/31/2007 11:48 PM (GMT -7)   
Ides is right, but don't worry, and if it does happen there's humira that's pretty much the same thing but a diff protein.
I believe it's remicade that's has the rat protein. I can't remember. Some can't even use Remicade b/c of that, so your lucky you can use it :)
I'm glad it's working for you btw :)
Male DX with CD May 2006 @ age 22, Colonoscopy and SBT
Taking Prednisone 35mg, Pentasa 1000mg 3xday, Atenolol 25mg for fast heartbeat and Restoril 30mg for the sleepless nights (thanks Pred!)


teddybearweiser
Veteran Member


Date Joined Oct 2004
Total Posts : 3042
   Posted 11/1/2007 2:56 AM (GMT -7)   
Hi I totally agree with Ideas, Don't worry about it. Enjoy the remission.
Hi, I am teddybearweiser, I am a male.
I was diagnosed with crohns disease when i was admitted to the hospital
in 1992, in Jan of 1993 I was back in the hospital for surgery for my crohns. I had part of my right colon resectioned with ilecolonstomy.
 My GI doctor has me on Asacol, Dicyclomine,Imuran,Celebrex and Remicade. B-12 injection once a month.
My Internest doctor has me on Lisnopril-HTCZ and Folic Acid. Diagnosed
with Osteoarthritis July 2007
 


JudyK89
Veteran Member


Date Joined Dec 2006
Total Posts : 1986
   Posted 11/1/2007 7:01 AM (GMT -7)   
Ides said...
In my unscientific opinion, those that are builders of antibodies seem to have other autoimmune issues/diseases or have other complicated histories or conditions. Just my observation from reading a lot of posts here. Hopefully, Remicade will continue to do its magic for you for a long, long time.
Nope, no other autoimmune process going on here, nothing complicated, just CD for 30+ years. 
Judy
49 years old, Crohn's Disease   
Six resection surgeries, permanent ostomy, adverse reactions to Remicadeback on 6MP for maintenance, hoping for a long remission from this last surgery. 
 
 

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