Gold standard for crohns diagnosis vs UC

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Regular Member

Date Joined Sep 2006
Total Posts : 246
   Posted 11/2/2007 6:28 AM (GMT -6)   
hello, i recently developed a fistula which im going to get removed but it has me thinking based on others comments that i may have crohns vs UC, my original diagnosis. my question is, is there a gold standard for testing whether one has crohns vs UC. im sure blood work plays a part but not clear on this. thanks so much for the help!
- 29 y/o single IT professional male residing in Northern VA, USA
- UC Diagnosis - April, 2006 - Symptoms were sudden and drastic
- GI did not determine type of UC as I was too inflamed during the c-scope
- Completed 3rd Prednisone taper on 4/13/07 - Tapered from early January through mid-April after being hospitalized from a bad flare with anemia & severe joint pain.
- Currently in remission and enjoying life again since getting out of the hospital in early Jan 07' from a nasty flare
- Survive on 4 Colazal/day, 1 GNC Multivitamin, occassional Fish oil & Primal Defense Probiotics
- Enjoy the outdoors, relaxing and spending time with family and friends

Veteran Member

Date Joined Mar 2006
Total Posts : 1169
   Posted 11/2/2007 6:37 AM (GMT -6)   
Well, the traditional standard is skip areas of inflammation (in CD) versus continuous inflammation throughout colon (in UC); depth of inflammation (it goes deeper into bowel wall in CD); and fistulas (not usually rpesent in UC.) Plus SBFT or pill cam can spot inflammation in small bowel, which indicates Crohn's rather than UC, which is confined to the colon. Otherwise the basic symptoms (D, cramps, etc>) are pretty similar.

Regular Member

Date Joined Oct 2007
Total Posts : 235
   Posted 11/6/2007 1:42 PM (GMT -6)   
I think Prometheus Labs specializes in using a series of blood tests to not only diagnose IBD, but to also differentiate between the types (Ulcerative Colitis or Crohn's).

Check this out...

What's really interesting is the sample test results shown on page 10. Make sure you check with your health insurance provider prior to having this test done, though. I didn't even know my GI was going to order this test until I got a "Claim Denied" notice from my insurance company and a bill for 450 bucks from Prometheus Labs.

Veteran Member

Date Joined Oct 2004
Total Posts : 3932
   Posted 11/6/2007 10:15 PM (GMT -6)   
In practical reality, NO there isn't one. If you show classic Crohn's on a scope & biopsy maybe. That, BTW, is the exception here..

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