I am 5'8 (female) and was down to about 105lbs when I started Humira back in April, I am now at about 120lbs so the Humira definitely helped me gain weight. I stopped having as much D and the weight finally started coming back. Now I'm kind of concerned it won't stop. I am starting to be a little more careful about how much I eat beacuse I don't want to gain too much. I think bland foods were the easiest to keep down, wheat breads, mashed potatoes, noodles. Stuff like that. Hope your brother is feeling better soon.