Humira and Strictures?

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Regular Member

Date Joined Oct 2007
Total Posts : 54
   Posted 11/14/2007 5:15 AM (GMT -6)   
I met with my GI today, and he wants me to start Humira. However, he was concerned about my stricture, so he's going to check with his rep and find out if it is ok to take if you have a stricture.
Do any of you have strictures and take Humira?
Also, do you have any advice about starting this drug?

Regular Member

Date Joined Oct 2007
Total Posts : 289
   Posted 11/14/2007 11:56 AM (GMT -6)   
I take Humira and have a stricture,the Imuran decreased my inflammation alot,but my GI is hoping with the Humira,the inflammation will decrease more and he can widen the stricture with a scope. Good luck,sounds like we might be in the same boat. I never knew I had a stricture untill I had my scope. tongue

Veteran Member

Date Joined Jan 2003
Total Posts : 1130
   Posted 11/14/2007 12:07 PM (GMT -6)   
I think the original scare with anti-TNF treatments and strictures was that the rapid healing of the mucosal/drapid decrease of inflammation in regards to strictures could cause scarring/fibrostenotic strictures. I've read some studies that do not support this and many say it can be very helpful in decreasing the strictures.... unless of course the stricture is already a fibrostenotic/stricture cause from scar tissue.

If your uncomfortable with the biologics with stricturing disease, I would do research on anti-TNF treatments and firbostenotic strictures.

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