Imuran and 6MP do cause nausea in a number of people. That is the reason the prescript
ion bottle should say that it is to be taken with meals. Not just a cracker but a substantial meal. If I do not enough when I take mine I get nauseated. Immunomodulators like 6MP are usually prescribed to be taken as one dose during the day unless your doctor specifically orders something else. Many members here that experienced lots of nausea found that taking the med in the evening helped thwart the nausea side effect.
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