Imuran necessary before Humira - and/or during?

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Regular Member

Date Joined Aug 2007
Total Posts : 89
   Posted 12/12/2007 11:23 AM (GMT 0)   
I've been talking with my nurse practitioner. She really wants me to be on Humira, although my symptoms are currently not too bad. Everything else I've tried (entocort, pred, asacol)-I had reactions to them. She wants to start me on Imuran for probably six months, then move to Humira. I know I've read different things on here. Is it true that I should be on the Imuran first to suppress my immune system and have less likelihood of my body developing a resistance to the Humira? Do I need to stay on the Imuran all the while I'm on the Humira? She made it sound like I should only be on Imuran for no longer than six months. I know I've seen people on here that are on Imuran forever and a day and also people on Humira with no Imuran. She also said insurance likely won't approve Humira unless the Imuran is tried first.
Dx'd CD in August 2007 - 42-yr-old wife and mom
Bad reactions to Entocort, Prednisone and Asacol / Not sure what's next
Currently on Aciphex, probiotic, calcium and multi-vit; and Flovent (for asthma)

Veteran Member

Date Joined Dec 2006
Total Posts : 1986
   Posted 12/12/2007 11:32 AM (GMT -6)   
Why don't you try the Imuran for six months, and maybe it will work on its own? Personally, I know lots of people on here have been on the biologics without being on an immunosuppressant, but with your history of reactions, I would stay on the immunosuppressant if I had to go on them. My troubles all started when I was taken off the immunosuppressant while on Remicade.
Crohn's Disease   

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