I started Imuran Friday. I had tapered from 40 to the 30 of Prednisone. I just developed Crohn's the week of Thanksgiving and was in hospital 12 days.
My doctor told me he had been doctoring a long time and had seen so many wonder drugs come and go that he prefers to go this route because this drug has been around long enough. Actually, mine is Azasan, which is the same thing. Anyway, he then began my dosage a bit differently than yours. I started with 50 mg pills, but I am only taking 1/2 a pill a day. He does not start people on the full dose. He waits and sees how they tolerate.
So, as I posted yesterday, my bloodwork came back with the WBC at 3100. He said that could cause me not to be able to increase the Azasan. So, I had the blood work repeated yesterday and in 4 days my WBC went up to 6600. With that news, he told me to decrease the Pred. to 25 but not to increase the Azasan. That has to stay at 25. My next instruction is to call him the day after Christmas, and tell him how I am and he will tell me what to do next. However, that a.m. I am to drop the Pred to 20, and he said he may tell me to add the other 5 back that same morning, or he may not. He did not say whether or not I will increase the Azasan that day.
I also take 12 200 mg Asacol per day and a Rx iron since I am still anemic.
Hope this helps you in your hunt for info.
Btw, my WBC was at 10500 when I started Imuran, now it's at 9600, seems that it's kicking in for me just the last week or so.The blood work is usually every week for the first 4 weeks, then next 2 months every 2 weeks, and after that once a month I was told.