Here is what I know about
the sweat test results:-
under 40 is normal, 40-60 is a borderline/grey area, over 60 is almost certain.
As far as I am aware a test result of 33 is definately a normal level and would not indicate CF.
For full CF, a person would need 1/2 gene from each parent. Each parent can either pass on half a gene with no faults, or half a gene with faults. If they have just 1 half of the faulty gene from one parent but a normal gene from the other parent, then this would make the offspring a carrier of CF. The CF fault cannot be activated with only half a gene, you need both halves to make a full one.
But then, this is where it gets complicated. Over the years the CF gene has mutated and changed. So far they can only test for a handful of the hundreds of different mutations of the gene. Even a full genetic panel can only test for a percentage of the mutations. I think the common mutations panel check for the top 20 most common. So, it's possible doing a genetics panel, might not tell you anything.
But, with a sweat test result of 33, and only one of the common genes, your son maybe a carrier, but I doubt he'd have full CF, and therefore shouldn't experiance any more problems with his health than someone who doesn't have any CF genes at all.
Hope this helps,
I wish you well with the rest of the testing, and hope your son grows into a healthy happy person:)
Moderator of the Cystic Fibrosis Forums
Diagnosed with: Cystic Fibrosis, Asthma, ABPA, Clinical Depression, Mild Liver Cirrohsis, Mild Osteopenia, Erythema Nodosum. Waiting for final diagnosis on Muscular Dystrophy type symptoms.
Medication: Creon 10,000, Flucloxacillin, Vitamins A,D+E, Serevent, Salbutamol, Paracetamol, Ondansetron, Nefopam, Ursodeoxycholic Acid, Saline neb/PEP system, Mirtazapine,slow-sodium, Skandishake and Fresubin.
Had a Port-a-cath fitted on chest wall since Nov 05
Sometimes, I feel that I should go and play with the thunder-In The Shadows by The Rasmus
Post Edited (Darkies Gem) : 11/13/2008 2:45:39 PM (GMT-7)