My sister is 34 and a cf patient. I am 38, so I grew up with her dealing with the cf. I think the most important thing is to let your daughter try things and not limit her because she has this disease. My sister always participated in PE at school and she played all the sports as she got older with no problems. I know there are lots of things that seem scary, but just try not to limit her. Her body will tell her and you what she can and can't do. Just think, your daughter is only two, there will undoubtedly be breakthroughs in her lifetime. Treating her the same as everyone else will go a long way toward her self-esteem, too. I now have a 6 year old son, and to advise you not to baby your child is difficult as I try to baby my son who is quite healthy. I think it's just a mom thing to want to protect, but your child takes cues from you. If you seem to her like she should be tired after a few minutes of playing, she will become tired. Enjoy your child!