I need an antidepressant med without so many side effects

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Date Joined Apr 2006
Total Posts : 733
   Posted 12/25/2007 7:02 PM (GMT -6)   
I have Ulcerative Colitis and now arthritis and body pain.  I am frustrated with it all.  I was prescribed Cymbalta and Lyrica.  I have been having gut problems so I only tried the Cymbalta but it made me jittery, extreme nausea and I couldnt sleep.  I took it 3 days and I hardly ate those days and hardly slept and couldnt take that any more.  I did feel less stress and easygoing though.  Then I found some articles about getting off Cymbalta and horrible withdrawls.  I am scared to try the Cymbalta again.  I am very sensitive to meds.  What antidepressants work for you?  Or any other advice appreciated.
Diagnosed with Left-sided Ulcerative Colitis 1995 at 15
Tried: Prednisone, Rowasa & Hydrocortisone Enemas, Proctofoam, Sulfasalazine, Asacol, Probiotics, Fish Oil, Canasa, Enotcourt, Colazol, Proctocort, Anamantle, etc...
Diagnosed with Ulcerative Proctitis with rectal fistula in 2004, put on Remicade
2007:Increased Remicade dosage-660mg every 6 weeks,diagnosed with Psoriatic Arthritis & Fibromyalgia
Current meds: Remicade 660mgs every 6 wks ( had a reaction will start Humira in 6 weeks) Lomotil, Darvocet, Clorazepate

Another Day
Veteran Member

Date Joined Mar 2007
Total Posts : 1055
   Posted 12/25/2007 7:31 PM (GMT -6)   
I have taken Celexa for a number of years with no problem, but you and I have different health problems.  You might mention it to your doctor.  I know for those of us who have several health issues, sometimes it can be hard to find a medication for one illness that will work with the medication for another.
Good luck to you!

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Epilepsy, asthma, GERD, depression, hypothyroidism, tinnitus

Veteran Member

Date Joined Oct 2005
Total Posts : 4031
   Posted 12/25/2007 7:42 PM (GMT -6)   

Hi princesscolon, I am sorry things are going so rough for you now. eyes

Most antidepressants are going to have side-effects when you stop taking them after long-term usage.  It is important that you know that these are just side-effects and not withdrawls as antidepressants are not addictive...there is a big difference between the two, many people are not informed regarding this due to so much conflicting information on the Internet.

Antidepressants work different for each one of us.  So I could tell you that Zoloft worked well for me and that Effexor XR is working great for me now but you may not get the same benefit from these medications.  This is due to our having different body chemicals and how we break down, process medications that effect the way they work.  Cymbalta is the newest antidepressant on the market so, doctors are really pushing that one as they are getting samples from drug reps and such.

What my recommendation would be if you do decide to restart an antidepressant is when you have problems, call your doctor.  Like when your not sleeping, after day 2; call the doc and try to get something to help you sleep.  Sometimes when first starting an antidepressant you may feel sick to your stomach, or like a motion sickness feeling, if it is an extreme thing and you don't feel like you can handle it then call your prescribing doctor and let them recommend another antidepressant for you...

Please post again and let us know how your doing and keep us updated...

Co~Mod: Depression
Moderator: Heart & Cardiovascular Disease

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