wellbutrin and elevated liver enzymes?

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confusedgirl22
Regular Member


Date Joined Dec 2007
Total Posts : 228
   Posted 4/10/2008 4:02 PM (GMT -7)   
Hello. 4 years ago I was diagnosed with autoimmune hepatitis. I was on prednisone for 2 years. My liver enzymes have been normal for 2 yrs. Yesterday I got blood work done and my liver enzymes were slightly elevated again. I'm really scared. I started Wellbutrin a month ago. Do you think Wellbutrin has anything to do with the elevated liver enzymes? My family doctor (not my psychiatrist) told me to stop the Wellbutrin and to get blood work in 2 weeks to see how the enzymes are. I know I should ask my psychiatrist before completely stopping wellbutrin. I will call her tomorrow. Just wondering has anyone else had elevated liver enzymes on Wellbutrin? I hope the autoimmune hepatitis isn't back. I don't want to go on prednisone again..it made my face puffy! Thanks!

getting by
Forum Moderator


Date Joined Sep 2007
Total Posts : 40578
   Posted 4/10/2008 5:16 PM (GMT -7)   

Hello Confused,

I would seriously talk to the psychiatrist before stopping the wellbutrin.  He might want you to go off slowly.  I did read that people with liver disease should start off slowly with it.  But I didn't read anything about it being hard on the liver.  Do you take tylenol a lot or anything?  That can elevate your levels.  Other than that I would just make sure that you call your psychiatrist as planned and talk to him.  Do you drink alcolhol?  That can also be hard on your liver.  I hope that you don't have hepatitis.  You might want to go to their forum and ask questions.  They would probably have some answers for you.

Hugs, Karen


  Moderator-Depression
 
fibromyalgia, Chronic fatigue, depression,allergies


confusedgirl22
Regular Member


Date Joined Dec 2007
Total Posts : 228
   Posted 4/10/2008 5:31 PM (GMT -7)   
Hi getting by. I don't have hepatitis. I have autoimmune hepatitis.. it's not contagious and I can't pass it on with my blood and it's not a virus. My immune system attacks my healthy liver cells. I don't take tylenol ever since I found out I had it. I don't drink too often anymore either. I haven't had this autoimmune hepatitis for 2 years. But I hope it's not back. :-( I will call my psychiatrist tomorrow.

ShynSassy
Veteran Member


Date Joined Dec 2005
Total Posts : 3036
   Posted 4/14/2008 5:01 AM (GMT -7)   
Bump
Shy


Mod- Depression

Chronic Depression, Panic Attacks,Anxiety Attacks,Anorexia

Please remember,I am not a professional..I am just a person who is also fighting depression.


quietpain
Regular Member


Date Joined Apr 2008
Total Posts : 112
   Posted 4/22/2008 11:43 AM (GMT -7)   
I don't know structure of the drug as with tyes. I rememger if when I took it where it would digested Buproi

on(walbrutrin ,all dose types) w/buspar commbo.

millwalk
New Member


Date Joined Jul 2008
Total Posts : 2
   Posted 7/3/2008 8:22 AM (GMT -7)   
Hi,

I am new to this site, but you might want to know that I have had a diagnosis of autoimmune hepa*** and have been taking Wellbutrin with no adverse effects. I was taking a small dose - 100 mg. at the time I was diagnosed and henceforth. Unfortunately, I felt the need to increase the dosage this past month as it really wasn't effective for me in the midst of an increase in stressful life events. I am currently in discussion with my physicians about what is safe. This past month I took 200 mg. SR and that is getting closer to meeting my need to not get depressed. I now want to know if it is okay to take 200 or 250 for the longer term without risk to my liver. I have been stable with my blood tests, shown some improvement in my last biopsy, but do have liver damage that originally placed me in a stage of cirrhosis. I am not sure I am out of the woods with the stage of my liver damage, but have been feeling well and"normal" on a course of 50 mg Azathriopine a day. I originally started on Prednisone with the confirmation of my diagnosis (3 months) and have remained on the Azathriopine since. I was diagnosed in about March 2007. I am a 53 y o female.

I'll keep you posted.

Millwalk

getting by
Forum Moderator


Date Joined Sep 2007
Total Posts : 40578
   Posted 7/3/2008 9:39 AM (GMT -7)   
Hi Millwalk,

I just wanted to welcome you to Healing Well.

I think that you will find this a wonderful place to visit.

Keep posting,

Karen
  Moderator-Depression
 
fibromyalgia, Chronic fatigue, depression,allergies


millwalk
New Member


Date Joined Jul 2008
Total Posts : 2
   Posted 7/3/2008 1:49 PM (GMT -7)   
Thanks.

getting by
Forum Moderator


Date Joined Sep 2007
Total Posts : 40578
   Posted 7/3/2008 3:13 PM (GMT -7)   
I am happy that you have been feeling better Millwalk. I am sorry though that you have been having problems with your liver. My sister had cirosis (sp) of the liver. I know that it was a hard time for her. I hope that you continue to feel better and take the welbutrin with success.

Have a wonderful evening and a wonderful fourth.

Hugs, Karen
  Moderator-Depression
 
fibromyalgia, Chronic fatigue, depression,allergies


confusedgirl22
Regular Member


Date Joined Dec 2007
Total Posts : 228
   Posted 7/7/2008 4:14 PM (GMT -7)   
Hello millwalk. Welcome to the site. I am sorry to hear you also have autoimmune hep. I'm glad you are feeling better. I was diagnosed almost 4 yrs ago. My enzymes were high the first 2 yrs I was diagnosed but then became normal since I took prednisone. Except for that day after I started taking wellbutrin I checked them they came up again. I've been off prednisone for 2 yrs no. I checked my enzymes about a month ago and they are normal. I will see how they are this week. I'm taking 250 mg of Wellbutrin and 100 mg Zoloft. I hope you don't have a problem with wellbutrin and are doing well. Keep me posted! Take care!
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