I'm new to these forums but joined because I have a couple of questions about what has happened with me lately...
about three years ago, I was diagnosed with depression when out of the TOTAL blue, I was hit with the inability to concentrate, I wasn't eating, I had terrible anxiety, I was waking up earlier than normal with anxiety... etc. Before this, I was a healthy 26 year old guy, who had graduated college, and led a totally normal life.
I originally had no idea that it was even depression, but after MRI's and catscans, we figured it out, and I was started on Lexapro. Lexapro did nothing for me. We then tried Zoloft. Again... it did nothing for me. At this point, I was truly freaking out. I felt that my girlfriend of the time would wind up leaving me since I was "crazy", I thought I'd lose my job... etc. I marched forward and decided to try Effexor XR after my psych doc suggested it. I started out on 75mg, and voila, I felt much better. 2 months went by, and I had relapsed. Went up to 150mg, felt great for another two months. This continued until I was at 225mg per day and Remerol at night. I took the Remerol for a couple of months, and gained a TON of weight (I needed some weight, but not so much). I eventually stopped taking the Remerol on my own, and worked my way down to 150mg of Effexor. While on the 150... I was living life to about 90%+ as the Effexor was truly making a difference for me. I got engaged to my girlfriend, bought a house, got married last July... all was well. The only downside to the Effexor was lack of sexual drive, and increased blood pressure. To think and function on a normal basis, these side effects were very very minor to me overall.
about two weeks ago, like a freight train, all of the initial symptoms came back. My concentration is terrible, zero short term memory, not eating, waking early, etc. I called the doctor and asked for 37.5mg of Effexor more per day. It helped ONE night and I felt like I was headed in the right direction. But the next day was upsetting since I felt like I was getting worse. A week ago, we upped me to 225mg of the Effexor... but to no avail. I feel like I am getting worse as the days go by.
I am terribly frightened that since the other drugs we tried didn't work, and now that the Effexor doesn't seem to be working, that I will always have to feel like this.
My doc assures me that he has many many different options and combinations that could help me out. I guess I should believe him considering he got me through the last three years relatively symptom free. I met with him yesterday and he decided to take my Effexor down to 150mg for 3 days, then switch over to Cymbalta 60mg per day. Does ANYONE out there have any experience or know of anyone who Cymbalta has worked for after Effexor had stopped being effective? Any input is appreciated. I am praying to God every day that this is going to help me like the Effexor used to.