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Anne_76
New Member


Date Joined Feb 2008
Total Posts : 15
   Posted 6/4/2008 1:20 PM (GMT -6)   
Hi, I was wondering if anyone here is on Deplin? I started on it today to take along with my Wellbutrin. I am wondering what to expect, time frame, side effects, all that. I have read about it but reading the warnings and stuff isn't the same as hearing from other people who have taken it.

Thanks
The center of the problem never knows it's the problem, all it knows is it has a problem with all the problems that have a problem with it, what it doesn't realize is if it wasn't a problem all the other problems wouldn't be a problem.


getting by
Forum Moderator


Date Joined Sep 2007
Total Posts : 34368
   Posted 6/4/2008 7:04 PM (GMT -6)   
Hi Anne,

I don't know anything about deplin, other than what I read on the forum today. Was it folic acid? And I think that I read that it helps other medications work better. If I am wrong, please correct me, I am counting on my memory and that just doesn't cut it. I will have to reread that other post.

Any way, I hope that you had a wonderful day today.

Hugs, Karen
  Moderator-Depression
 
fibromyalgia, Chronic fatigue, depression,allergies


stkitt
Forum Moderator


Date Joined Apr 2007
Total Posts : 32601
   Posted 6/4/2008 7:14 PM (GMT -6)   

I believe Karen is right on that.  I am not on it and will be curious to see what you think after you have been on it for a bit.

Keep on posting

Kitt


 

Kitt, Moderator: Anxiety, Panic & Depression 
*~*
http://www.healingwell.com/donate *~*
Not a mental health professional of any kind
It is health that is real wealth and not pieces of gold and silver.~Mahatma Gandhi~


Anne_76
New Member


Date Joined Feb 2008
Total Posts : 15
   Posted 6/5/2008 8:33 AM (GMT -6)   
Ok there is a website, I hope it's ok that I tell you here, it's deplin.com, it sounds really great, it's not folic acid, I think what my doc said was LIKE a super charged folic acid, she was very excited about it, anyway it helps your antidepressant work better, I will keep you guys up to date on how I am feeling over the next month, I read yesterday that it can take like two weeks before you start feeling it, Ill be the lab rat.

Yesterday was sorta an up day for me, I was happy and had energy, I feel good this morning but I have so much running to do, paying bills, driving all over middle Tennessee, going to the grocery store, getting my kids signed up for summer classes, getting tags renewed, and yes I am registering to vote today, so lets see how I feel this afternoon, did I tell you that I am doing all this with a 9 yr old, a 7 yr old, and a 1 yr old. This should be lovely. Maybe my mood will hold. Pray for me!
The center of the problem never knows it's the problem, all it knows is it has a problem with all the problems that have a problem with it, what it doesn't realize is if it wasn't a problem all the other problems wouldn't be a problem.


sheryl=jk
Veteran Member


Date Joined Oct 2004
Total Posts : 4083
   Posted 6/5/2008 9:03 AM (GMT -6)   
Good Luck Anne, looks like you have a busy day, keep us posted,
thanks for the heads up on the thread... smurf ..
 
God Bless,and have a Great Day!!.......Love.....Sheryl
xcema,hypermobile,Chronic Bronchitus,Fatigue,Positive ANAFibro-05--Had surgery on left & right knees 06, Interstial Cystitis-06  implanted Interstim-06 hysterectomy & IBS-06 Arthiritus-04 Depression-04GERDS/ Hiatial hernia -07   Anxiety-07 Gastroparesis-08--Occasional Migraines Reglan,Protonix,Prozac,Wellbutrin,Erthomyicin,klonipin,occasional phernergan Im marrried 2 children, one with mild autism, Bipolar(8), she takes Abilify, Buspar, Celexa Son(13) is bipolarw/migraines, Topamax, ZantacGod plz grant me the serenity to accept the things I cannot change, the courage to change the things I can, and the wisdom to know the difference..." Plz help HW to help others by donating: http://www.healingwell.com/donate/


stkitt
Forum Moderator


Date Joined Apr 2007
Total Posts : 32601
   Posted 6/5/2008 9:59 AM (GMT -6)   

Here is hoping your mood stays elevated and my yes I remember the days I ran around with 4 little kids in the car so I know where your coming from.

Do keep us posted on the med, I am very curious to see how you do on it.  You are our guinea pig.............. devil

Hugs
Kitt


 

Kitt, Moderator: Anxiety, Panic & Depression 
*~*
http://www.healingwell.com/donate *~*
Not a mental health professional of any kind
It is health that is real wealth and not pieces of gold and silver.~Mahatma Gandhi~


sheryl=jk
Veteran Member


Date Joined Oct 2004
Total Posts : 4083
   Posted 6/5/2008 11:02 AM (GMT -6)   
i went and visited the site, in was very informative. Just wish I had the money to try it, im sure my insurance would charge the highest co-pay, or not cover it at all. sad
 
God Bless,and have a Great Day!!.......Love.....Sheryl
xcema,hypermobile,Chronic Bronchitus,Fatigue,Positive ANAFibro-05--Had surgery on left & right knees 06, Interstial Cystitis-06  implanted Interstim-06 hysterectomy & IBS-06 Arthiritus-04 Depression-04GERDS/ Hiatial hernia -07   Anxiety-07 Gastroparesis-08--Occasional Migraines Reglan,Protonix,Prozac,Wellbutrin,Erthomyicin,klonipin,occasional phernergan Im marrried 2 children, one with mild autism, Bipolar(8), she takes Abilify, Buspar, Celexa Son(13) is bipolarw/migraines, Topamax, ZantacGod plz grant me the serenity to accept the things I cannot change, the courage to change the things I can, and the wisdom to know the difference..." Plz help HW to help others by donating: http://www.healingwell.com/donate/


Anne_76
New Member


Date Joined Feb 2008
Total Posts : 15
   Posted 6/14/2008 12:05 PM (GMT -6)   
I am sorry I haven't been back in a while, everything has been very busy with my children being out of school, last week they had an art class at the center here in town and we were out alot. I am only on week two and haven't really felt any differently. I feel as though I am stuck about half way up a pole, I am not down really but not up either, just kinda in the middle. Maybe it's because I haven't really had time to think, it seems like everyday there is something I have to do, but this next week we have nothing planned excepts for trips to the park near here to play. Anyway, it says that it takes about two weeks so I am hoping it will boost next week, we will see what happens. I will keep you updated. I am also trying to loose weight so that may be playing part in my recovery, along with the prices of everything going up, I seem to worry about everything, yesterday in the grocery store I nearly started crying while looking at the prices on the baby food, I finally gave up and just walked away.
The center of the problem never knows it's the problem, all it knows is it has a problem with all the problems that have a problem with it, what it doesn't realize is if it wasn't a problem all the other problems wouldn't be a problem.


JES22061
New Member


Date Joined Jun 2008
Total Posts : 1
   Posted 6/15/2008 12:08 PM (GMT -6)   
Two days ago, I started taking Deplin in conjunction with my Lexapro which I have been on for the last ten days. My doctor prescribed it as the Lexapro was not totally working yet. I found that it has improved my concentration and also my moods. I have not developed any new side effects since starting on it.

Since being on the Lexapro though, I have been having the worse headaches. However, this may be due to the blood pressure medication that she also prescribed ten days ago.

I will keep you informed on how it is working for me.

Jill

getting by
Forum Moderator


Date Joined Sep 2007
Total Posts : 34368
   Posted 6/15/2008 1:17 PM (GMT -6)   
Hello Jill,

Welcome to Healing Well. I am so happy that you have posted.

Sometimes when we start more than one medication at a time, we aren't sure which is causing what. I hope you figure your headaches out. I hope that your anti depressants work good for you. I didn't realize that the dephlin could work so fast.

Thank you for your input, keep posting.

hugs, Karen
  Moderator-Depression
 
fibromyalgia, Chronic fatigue, depression,allergies


sheryl=jk
Veteran Member


Date Joined Oct 2004
Total Posts : 4083
   Posted 6/15/2008 3:02 PM (GMT -6)   
I went to my new phych on the 12th, he never heard of deplin, I wasnt crazy about, him, i just wan to keeo my kids on what they are on. me will see????
 
God Bless,and have a Great Day!!.......Love.....Sheryl
xcema,hypermobile,Chronic Bronchitus,Fatigue,Positive ANAFibro-05--Had surgery on left & right knees 06, Interstial Cystitis-06  implanted Interstim-06 hysterectomy & IBS-06 Arthiritus-04 Depression-04GERDS/ Hiatial hernia -07   Anxiety-07 Gastroparesis-08--Occasional Migraines Reglan,Protonix,Prozac,Wellbutrin,Erthomyicin,klonipin,occasional phernergan Im marrried 2 children, one with mild autism, Bipolar(8), she takes Abilify, Buspar, Celexa Son(13) is bipolarw/migraines, Topamax, ZantacGod plz grant me the serenity to accept the things I cannot change, the courage to change the things I can, and the wisdom to know the difference..." Plz help HW to help others by donating: http://www.healingwell.com/donate/


stkitt
Forum Moderator


Date Joined Apr 2007
Total Posts : 32601
   Posted 6/15/2008 3:09 PM (GMT -6)   

Hello Jill,

Welcome to HealingWell and the Depression Forum.  If you would like to start your own thread that would be great and we can all get to know you better :)

I will be interested in the Deplin and how you think it is working a few weeks down the road. 

Sheryl, this is a fairly new med and I am still wonderinf myself why I have to use another med to make the med I take work better............but I am not a scientist.  redface

Hugs Kitt


 

Kitt, Moderator: Anxiety, Panic & Depression 
*~*
http://www.healingwell.com/donate *~*
Not a mental health professional of any kind
It is health that is real wealth and not pieces of gold and silver.~Mahatma Gandhi~


sheryl=jk
Veteran Member


Date Joined Oct 2004
Total Posts : 4083
   Posted 6/15/2008 3:57 PM (GMT -6)   
My new pdoc seemed to think it sounded redundant, he said, even tho he didnt know what it was.  He up my wellbutrin, and wants to up the
prozac, and get me off the kloinpin.
 
God Bless,and have a Great Day!!.......Love.....Sheryl
xcema,hypermobile,Chronic Bronchitus,Fatigue,Positive ANAFibro-05--Had surgery on left & right knees 06, Interstial Cystitis-06  implanted Interstim-06 hysterectomy & IBS-06 Arthiritus-04 Depression-04GERDS/ Hiatial hernia -07   Anxiety-07 Gastroparesis-08--Occasional Migraines Reglan,Protonix,Prozac,Wellbutrin,Erthomyicin,klonipin,occasional phernergan Im marrried 2 children, one with mild autism, Bipolar(8), she takes Abilify, Buspar, Celexa Son(13) is bipolarw/migraines, Topamax, ZantacGod plz grant me the serenity to accept the things I cannot change, the courage to change the things I can, and the wisdom to know the difference..." Plz help HW to help others by donating: http://www.healingwell.com/donate/


Gerald F. Nowatzke
New Member


Date Joined Aug 2008
Total Posts : 1
   Posted 8/22/2008 9:00 AM (GMT -6)   
I’m glad to find this discussion of Deplin as I can add a few things from my experiences as well as a few questions.

I started taking Deplin as part of Stage III Clinical trials of the product in Feb 2007, and have been taking it since that point.

In terms of effect it takes about 5 days. The premise of the product is that it compensates for a defect in the CH5 gene which is involved in foliate metabolism
which is critical to neurotransmitter production. about 10% of the general population have is defect, while 45% of those with clinical depression have it.
I was taking Lexapro when I started taking Deplin. It seemed to give me a large lift in mood and functionality that lasted several months and ended my depression.

On possible side effect of Deplin is sleep disturbance: I keep waking up every 2 or 3 hours.


I stopped taking Lexapro about 6 months ago as the depression ended about a year ago. I've continued taking Deplin as part of the study but since that ended
I have to pay the $114 a month myself and with no insurance that a lot of money. So I'm going to stop taking it and see what happens.

In theory if I don't have the genetic defect it shouldn't matter.

Does anyone know of a drug company trade group that helps low income people pay for medications?

getting by
Forum Moderator


Date Joined Sep 2007
Total Posts : 34368
   Posted 8/22/2008 12:16 PM (GMT -6)   
I think that pfizer will help.

Good luck,
hugs, Karen
  Moderator-Depression and fibromyalgia
 
fibromyalgia, Chronic fatigue, depression,allergies


sheryl=jk
Veteran Member


Date Joined Oct 2004
Total Posts : 4083
   Posted 8/22/2008 1:13 PM (GMT -6)   
I was gonna say the same thing the maunfaturer
usally has programs to help people who have no insurance or cannot afford it.
 
God Bless,and have a Great Day!!.......Love.....Sheryl
xcema,hypermobile,Chronic Bronchitus,Fatigue,Positive ANAFibro-05--Had surgery on left & right knees 06, Interstial Cystitis-06 Spondlylosis/Disc Degernation Disease severe arthitis lower back -08,implantedInterstim-06 hysterectomy & IBS-06 Arthiritus-04 Depression-04GERDS/ Hiatial hernia -07   Anxiety-07 Gastroparesis-08--Occasional Migraines
 Reglan,Protonix,Prozac,Wellbutrin,Erthomyicin,klonipin,occasional phernergan, loratab, zanaflex  marrried 2 children, 1 with mild autism, Bipolar(9),  Abilify, Buspar, Celexa Son(13) is bipolarw/migraines, Topamax, ZantacGod plz grant me the serenity to accept the things I cannot change, the courage to change the things I can, and the wisdom to know the difference..." Plz help HW to help others by donating: http://www.healingwell.com/donate/


stkitt
Forum Moderator


Date Joined Apr 2007
Total Posts : 32601
   Posted 8/22/2008 11:32 PM (GMT -6)   

Thank you for sharing your information about Deplin.  I know many have been interested in this medication.

I see it comes with a high price tag and I hope you can access help in obtaining the drug at a reduced rate.

Kitt


 

Kitt, Moderator: Anxiety/Panic & Depression
& GERD  Forums
*~*
http://www.healingwell.com/donate *~*
Not a mental health professional of any kind
It is health that is real wealth and not pieces of gold and silver.~Mahatma Gandhi~
Clickable Link: Anxiety-Panic Resources


Georgie Girl
Regular Member


Date Joined May 2008
Total Posts : 319
   Posted 1/11/2009 5:56 PM (GMT -6)   
Just wanted to post that our pdoc added Deplin to my son's regimen and to mine. I didn't notice a big difference in the effectiveness of my drug cocktail but my son has noticed improved mood.
 
Our insurances don't cover, they consider this a supplement, not a medication.  The cost is about $65 but our doc gave us a discount card that makes it $46 or so. 



Georgie Girl
 
Bipolar, Anxiety Disorder, Rheumatoid Arthritis


getting by
Forum Moderator


Date Joined Sep 2007
Total Posts : 34368
   Posted 1/11/2009 6:56 PM (GMT -6)   
Hi Georgiagirl,

I am glad to hear that the dephlin is working for your son and for you. Thank you for the information on it. I didn't realize that it was considered a supplement instead of a medication.

Have a great day!

Hugs, Karen
  Moderator-Depression and fibromyalgia
 
fibromyalgia, Chronic fatigue, depression,allergies


2BSunny
New Member


Date Joined Sep 2009
Total Posts : 1
   Posted 9/26/2009 11:43 PM (GMT -6)   
yeah  Hi
I have been suffering great stress in my life and I decided to go on meds. I've been taking deplin and sertraline for 3 weeks. I felt the difference in one day with the sertraline on the first week. On my follow up with my Dr. she recommended some vitamins to take for stress and had some samples of deplin as it is a folate med food. I take the sertraline and deplin in the morning along with COq10 and vitamin D-3. WIth the intense stress I had the first week of the meds I did have mild side effects, headaches and  diahrrea but that subsided after a week. This is the best I feel it gives me so much energy and increased happiness. I feel like me again after 20 years of turmoil. I rejected anti depressants for years because of hearing about suicidal thoughts and its negativness to the drug. At this point in my life of so much counseling etc, I was finally ready to take something for my neuotransmitters, which like i said the sertraline i felt with in one day. THe doc said because I had such a disconnection in the neuotransmitters/ serotinin etc, it showed the anti depressent was working quickly. However the Deplin was taken a week later with the sertraline and my mood, energy hit is high in such a great way. Also I've been on a samples of the Deplin as i will run out next week.  So I will have a week with out it before I see my doctor and want to see the difference of just being on andidepessent without Deplin, as the say Deplin enhances the anti-depressant. I have also heard Deplin can work by itself and I hope I can just do this rather than depend on the anti-depressant as I'm not to keen on being on Meds. However being on Deplin can deplete your B-12 I understand so that is something i'm looking into adding to my supplement list.
Good luck I like Deplin no other side effects except positive effects. I feel like a New Person.
 
 
 

getting by
Forum Moderator


Date Joined Sep 2007
Total Posts : 34368
   Posted 9/27/2009 12:32 AM (GMT -6)   
Hi Sunny,

First of all welcome to the HealingWell depression forum.

I am so glad that the dephlin is working for you. It is wonderful that you wrote such a positive post. I am so happy that you are happy. Keep posting and spread some of this optimism around. We all could use it.

Hugs, karen
  Moderator-Depression and fibromyalgia
 
fibromyalgia, Chronic fatigue, depression,allergies


fritoburrito
New Member


Date Joined May 2009
Total Posts : 4
   Posted 11/5/2009 3:30 PM (GMT -6)   
Hello Deplin discussion ppls,

I wanted to chime in about Deplin and my experience. I was very skeptical about "super folate" doing anything for me. However, I trust my dr and decided to give it a try.

After about three weeks I did notice a difference. Nothing super-amazing but I did feel better. A little more energy, easier smile, a bit more "weight" lifted. You know what? I'll take it!!!

I do use it with my primary anti-depressant (Celexa, 40mg). My understanding is it works best with your main drug. I have zero side effects.

My opinion is that if your dr is ok with it, go ahead and give it a try. Unfortunately it is not a cheap drug, but not super expensive either. I've had good luck with the mfgr. sending me a gratis supply which got me by. Just takes a little paperwork and some patience. My doctor had tons of samples which got me started in the first place.

Good luck and God Bless.

Dennylee
New Member


Date Joined Feb 2011
Total Posts : 1
   Posted 2/9/2011 3:24 AM (GMT -6)   
Yes the first day I took Deplin I was healed.I crap you not.I have had depression for 33 years
I take 60 milligrams a day of Cymbalta and I feel like I am on a Magic Carpet Ride I don't sleep much but I feel Good Thanks Deplin


I'm even calling my Band Band Jed Deplin Denny Lee Cured at last
Thank you Jesus and The Great Spirit too!

alia
New Member


Date Joined Apr 2011
Total Posts : 2
   Posted 4/13/2011 11:33 PM (GMT -6)   
I am wondering if there are any updated viewpoints on Deplin. I am on Pristiq and Wellbutrin and have had numerous "poop outs" with various SSRI or SNRI's and convinced my psychiatrist to let me try Deplin. It was not cheap, insurance did not cover it but a RX card from store helped. I have checked UK, Canada etc prices and they don't seem to be markedly different. I am in an unusual situation as this is also the type of practitioner I am. So I have my script as of tonight and am really hoping it will help boost my neurotransmitters. I cannot find anyone I know who really knows much about it including my doc. Pristiq worked for awhile and is still somewhat working but it is lagging now a bit. Any advice/help?

getting by
Forum Moderator


Date Joined Sep 2007
Total Posts : 34368
   Posted 4/14/2011 9:32 AM (GMT -6)   
I take pristiq and abilify together. The abilify helps the pristiq to work better. I have never taken deplin, so I am not any help there. I hope this works for you. Let us know.

Hugs, Karen

PS welcome to the forum Alia.
Moderator-Depression and fibromyalgia


fibromyalgia, Chronic fatigue, depression, allergies
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