Hi Cowboy up,
Try to bare with your wife until she is done. I know that it is hard, but this has to be so important for the both of you. I would hate to see you give up now.
I am not sure how to answer your question. I guess it depends if the depression is situational or not. If it is situational, the situation is causing the stress. When the stress leaves the person usually gets better. But if it is a chemical imbalance, than the person needs medication to adjust it.
You will be able to tell when things slow down and your wife isn't under so much stress. If she gets better than you know that it was just situational. If not, then she needs to stay on medication. I know this really isn't answering your quesion, but it is the best that I can do for now.
But I think that the seratonin levels are related to stress in some situations. In others where it is hereditary, well, I think that medication is the best route to go. I have to be on medication for the rest of my life, though I can say that stress effects my level of depression. It would add to it so to speak.
I hope that this helps you some. I hope that you are having a good day/night.
Moderator-Depression and fibromyalgia
fibromyalgia, Chronic fatigue, depression,allergies