I am sorry that I can't help you with the Sam-e. But I am sure that there will be somebody coming along with some information on it.
I would like to welcome you to the depression forum. You have come to a good place and the members are so kind and compassionate here. There is also no judging that goes on here and everybody can understand how you feel. Please keep posting, I am sure that there will be somebody that can help you with your problem.
Supplements kind of work that way, they either work or they don't.
Best wishes for a wonderful day.
Moderator-Depression and fibromyalgia
fibromyalgia, Chronic fatigue, depression,allergies