Pristiq and tramadol

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dinda
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Date Joined Jun 2008
Total Posts : 13
   Posted 5/26/2009 9:51 AM (GMT -7)   
I was recently prescribed prestiq to help with my depression and nervous stomach. I take tramadol for back and hip pain. I was reading where you shouldn't take these two meds together. Is there anybody here that takes these two meds together? If you do have you had any reactions to them? I have taken them together and have been fine with it. I guess I'm just curious about mixing them?

Gemsi
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Date Joined Feb 2007
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   Posted 5/26/2009 12:47 PM (GMT -7)   
Hi there,

I don't take them both, but I do take Tramadol myself so just looking at the leaflet.
It says that you should tell your doctor if you're on other medicines that effect the nervous system things like; tranquillisers, sleeping pills, antidepressants, and other pain relievers such as codiene or morphine.
With some antidepreesants you may get convulsions (fits) when taken with tramadol, however it says that is very rare, and again something you need to discuss with your doctor.
SSRI's can be effected by Tramadol, but it says nothing about SNRI's which is what Pristiq is.

So, it is best to discuss with your doc what is best for you regarding the mix of these 2 medications, any concerns regarding side effects you are suffering from should be discussed with your doc straight away.

Sorry I just about got all broing stuff out of way now. Back to peoples actual experiances. Just wanted to let you know what the Tramadol leaflet said:)
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Ne Ne
Regular Member


Date Joined Apr 2008
Total Posts : 243
   Posted 5/26/2009 4:43 PM (GMT -7)   
I take both perstiq and tramadol. I don't take the tramadol every day but I've never had any problems. ttramadol works on what its suppose to and the perstiq does its job....


Dawn turn yeah
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Dx June 07 Crohn's take asacol 2x3 a day ,lotrel for HBP , omeprezole for stomach , potassium , calcium & Vit D , lomotil for lose stools , tramadol for pain , started humira in Feb 08 on 1 shot a week, vit-B 12 shots , crestor,off crestor,now pravastatin, pristiq, abilify,
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serafena
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   Posted 5/26/2009 7:41 PM (GMT -7)   
Dinda,

If you have any question, though, call up your pharmacist.

serafena
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THE HAPPY TURTLE
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Date Joined Mar 2009
Total Posts : 18746
   Posted 5/27/2009 3:51 AM (GMT -7)   
hi dinda, jamie here, on pristiq, basically the same info on my sheet here in australia, other anti-dep esp moai. some over the counter stuff too, so check with your pharmacist. they are the best to ask, and can inform you of the interactions, etc. hope you are feeling better. i am allowed panadol with codine, this is for my diabetic nuropathy. take care, jamie

dinda
New Member


Date Joined Jun 2008
Total Posts : 13
   Posted 5/27/2009 8:51 AM (GMT -7)   
thank you all for the replies. I have to get my prescription filled for my prestiq tomorrow if I can afford it. My insurance doesn't cover this med. I will talk to the pharmacist about taking tramadol with it.

THE HAPPY TURTLE
Elite Member


Date Joined Mar 2009
Total Posts : 18746
   Posted 5/27/2009 10:40 PM (GMT -7)   
wishing u all the best, and i hope u can somehow get the pristiq. i say this because i have been on the misery go round of meds for years now, and for once the pristiq is working well. cheers, jamie

lupetta
Regular Member


Date Joined Feb 2009
Total Posts : 38
   Posted 5/28/2009 7:38 PM (GMT -7)   
TRAMADOL AND PRISTIQ:  I get all my Rx's at the same drugstore and no one has mentioned a problem taking these 2 together.  I have been on Tramadol a yr (for fibromyalgia - tramadol is less destructive than the oxycontin and duragesic patch I had been on prior).  I've just started on Pristiq.
 
I have been on the merry go round of antidepressants over the years and had finally given up on them 3 yrs ago.  Instead, I started on anti-anxiety drugs (Ativan and/or Buspar) a yr ago. They've helped me more than the anti-depressants.  Yet...depression lingers.  I am going through a divorce now and have moved 2500 miles from the area I had lived in for 33 years prior...4 wks ago one of my Greyhounds died suddenly. Enough already!  Felt I had to do something - some kind of pro-active approach to the depression that has too long consumed my life.
 
Since I have just yesterday started on Pristiq I cannot say whether or not it will work for me; but I can say, it doesn't seem to be causing an interaction with the Tramadol.  Question your pharmacist when in doubt (better source of info for this than most drs are).
 
I wish us all happiness and eventual freedom from depression. smilewinkgrin

THE HAPPY TURTLE
Elite Member


Date Joined Mar 2009
Total Posts : 18746
   Posted 5/28/2009 11:22 PM (GMT -7)   
dear lupetta,
 
sorry for your recent loss, 3 months in with the pristiq, 200mg, very helpful and less sedating than the effexor xr. many healings, hope u feel better real soon, luv, jamie

lupetta
Regular Member


Date Joined Feb 2009
Total Posts : 38
   Posted 5/29/2009 6:47 AM (GMT -7)   
thanks Jaimee,
Life is just full of changes...some good, some not. I am SO happy for you that the Pristiq is helping. That gives ME hope. This approach is much better than the 'doing nothing' response...I know THAT one doesn't work.

Did you have nausea in the beginning w/Prestiq? I do, but it isn't bad enough to make me want to stop taking it. I hope this is the ONE that will finally work for me.

lupetta
Regular Member


Date Joined Feb 2009
Total Posts : 38
   Posted 5/30/2009 1:14 PM (GMT -7)   
Is anyone here having heartburn, a burning stomach sensation with Pristiq?? I am. Since I don't tend to have either problem, it's very noticeable. It started with the advent of Pristiq last wk and has continued ever since.

Thinking I may need a different antidepressant. THAT itself is depressing...I've just started this one 5 days ago.

THE HAPPY TURTLE
Elite Member


Date Joined Mar 2009
Total Posts : 18746
   Posted 5/31/2009 1:32 AM (GMT -7)   
dear lupetta, yeah a little qweezy the first week. does say that it may cause this initially, albeit try a few more days, if not definately seek medical attention. luv jamie.

dinda
New Member


Date Joined Jun 2008
Total Posts : 13
   Posted 5/31/2009 6:10 AM (GMT -7)   
Lupetta, I can't say if the pristiq causes heartburn or not because I have gastritis that it is taking a long time to heal up. I hope that you feel better soon. I am very happy that I can continue to take pristiq. I didn't think I was going to be able to afford it but found out my insurance will cover it if I go to the pharmacy. I can't order the 90 day supply through our insurance because they don't carry it that way but they will cover the cost at a regular pharmacy. I find this strange but I am not going to complain. I will just go to the pharmacy every month. Have a great day everyone.

lupetta
Regular Member


Date Joined Feb 2009
Total Posts : 38
   Posted 5/31/2009 10:15 AM (GMT -7)   
Pristiq is time-released and it seems to me, my experience is this: the severe burning is mild in the a.m. after taking it, but becomes severe by late afternoon. I have IBS-C, but burning in my stomach and sudden-onset heartburn are not symptoms I've ever had. I see my gastroenterologist in 3 days, so may pose the question to him at that time. The nausea doesn't bother me much (I was aware that is a common side-effect initially), but the abdominal burning alarms me. It's quite painful.

Faylin
New Member


Date Joined Jul 2009
Total Posts : 3
   Posted 7/22/2009 4:26 PM (GMT -7)   
Hello,
 
I take both Tramadol and Pristiq.  I hadn't been having any reaction whatsoever...but last week, that changed.  Apparently, I had a seizure.  I went to the ER and had a full work-up.  I was perfectly fine aside from the fact that I had a seizure.  I'm assuming that the seizure happened because of the medication interacting.  From what I have been told though, the potential for seizure is very small...a pretty rare side-effect.  I am going to be switching to a different antidepressant.  I was on zoloft for 7 years and never had an issue with it and the tramadol.  I only switched because the zoloft began to not work as well.

lupetta
Regular Member


Date Joined Feb 2009
Total Posts : 38
   Posted 7/22/2009 5:13 PM (GMT -7)   
Faylin: Wow...that sounds scarey! I ended up dropping the Pristiq and have been on Zoloft for the last month and a half. It's working - and I'm not having any adverse reactions w/Tramadol at all.

Meds work differently on different people, of course - for example, Pristiq works for my daughter in law, but made me so physically ill and uncomfortable that I stopped it. 'Pehaps' it was reacting to the Tramadol mixed with it...idk. I only know I'm not having adverse reactions anymore.

Faylin
New Member


Date Joined Jul 2009
Total Posts : 3
   Posted 7/22/2009 6:04 PM (GMT -7)   
I'm glad to hear that you're doing well on those medications, Lupetta. Zoloft was a wonderful medication for me for 7 years. I wish that it would have continued to be effective, but alas...it didn't lol I just find it a bit strange though with the seizure... I have been on this combination of meds with no alteration in dosage for almost a year. I take 50mg Pristiq and between 300-400mg Tramadol per day total. Never more than max of 8 tablets. I had never had an adverse reaction until last week. So, it does kind of make me wonder if it could have been something different after all.

stkitt
Forum Moderator


Date Joined Apr 2007
Total Posts : 32602
   Posted 7/23/2009 7:28 AM (GMT -7)   

Hey All,

Just my 2 cents..........I took tramadol with AD meds and I felt horrible on the combo.  Felt dizzy and sick.  I finally stopped with the tramadol and things did get better.  It took a long time though.

Each person reacts differently and I am so sorry to hear Faylin, I am so sorry you had a seizure on the meds.  I had a seizure many, many years ago from a medication I was on so it does happen. Mine was not a AD or Pain Med.

Be safe everyone.
Kitt
 

Kitt,
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lupetta
Regular Member


Date Joined Feb 2009
Total Posts : 38
   Posted 7/23/2009 2:04 PM (GMT -7)   
FAYLIN:  Have you quizzed your pharmacist about the possibility your seizure is related to Pristiq mixed w/Tramadol, or could it be another interaction...OR, could it be something unrelated to any meds you're on at all?  I'm wondering if you should see a neurologist to rule out something other than medications  as the culprit?
 
The amt of Tramadol I'm on is nothing compared to your prescribed amt.  I am actually sensitive to it - I'm allergic to codeine, and Tramadol - like codeine - is in the opiate family. I take 1 50mg tab early in the day and 1 before bedtime (I'm prescribed 2 at a time, but can't take that amt bc I'll react adversely), just to help me to be comfortable enough to sleep - hopefully.  Ibuprofen works better for my fibromyalgia than anything else ever has, but it caused such serious inflammation of my esophagus and stomach 9 yrs ago that I ended up in surgery over it.  Now I rarely take ibuprofen or other anti-inflammatories and certainly not on a daily basis.  Tramadol doesn't fix anything, but it helps w/the pain.
 
I hope you're able to track down the cause of your seizure.  I think it 'could' definitely be something not related to your meds.  Dig deeper until you have a satisfactory answer.  Don't blow it off!

killyourdream
New Member


Date Joined Mar 2010
Total Posts : 2
   Posted 3/29/2010 1:27 PM (GMT -7)   
Hi,
I took Pristiq(50mg) for 8 months, and was feeling great. My anxiety increased, due to a move and job change, and was given 100mg of pristiq, along with tramadol after a surgery. After a week of being on the two medications, I had a seizure. I stopped taking the tramadol, but continued my original dose of 50mg Pristiq - a month later, I had another seizure.

After countless test and doctors(i flew out of state to CA) It was concluded that my seizures are due to combo of the two drugs, which lowered my seizure tolerance - ect... BUT it was due to the interaction of the two drugs. I can no longer take either of the two drugs - so I was given Prozac.

SO I do warn you to stay away from the two, but at the same time, the Pristiq DID help me so much.

Best regards.

getting by
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Date Joined Sep 2007
Total Posts : 40571
   Posted 3/29/2010 2:25 PM (GMT -7)   
Hi Killyourdreams,

Welcome to the Depression forum. I am glad that you have joined us.

This is an older thread, from last year. So feel free to start a thread of your own and introducing yourself, if you feel comfortable with that.

Hope to hear more from you soon.

Hugs, Karen
  Moderator-Depression and fibromyalgia
 
fibromyalgia, Chronic fatigue, depression,allergies

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