long term effects of depakote

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New Member

Date Joined Sep 2009
Total Posts : 3
   Posted 9/10/2009 6:38 PM (GMT -6)   
I was misdiagnosed and was on depakote for 12 years for bipolar treatment. I have now been off of depakote for over 6 years. The last 2 years I have been diagnosed with collagenous colitis which is an inflammation of the intestines. Has anyone else experiences any long term gastrointestinal effects from the use of depakote? or has anyone developed gastrointestinal problems after discontinuing depakote?



Forum Moderator

Date Joined Apr 2007
Total Posts : 32602
   Posted 9/11/2009 10:22 AM (GMT -6)   

Good Morning,

I have no experience with depakote but hopefully one of our great members will have some helpful advice for you.

Take care,


Elite Member

Date Joined Mar 2009
Total Posts : 18576
   Posted 9/15/2009 6:42 AM (GMT -6)   
nor do i ruth. understand bi-polar very well though. hoping this siuation improves soon. welcome to the forum, i am sure someone will post with some info on it. in the meantime stay well and safe, and know that we are here for you. kind regards.
dx, mdd, severe borderline personality disorder.

Forum Moderator

Date Joined Apr 2007
Total Posts : 32602
   Posted 9/15/2009 9:59 AM (GMT -6)   
A few people have serious reactions to Depakote.

Here's a list of warning signs that may be the start of one of these problems. If you notice any of these things, call the doctor immediately:

- weakness, sluggishness, swelling of the face, loss of appetite, vomiting, yellowish eyes or skin, especially in a child under 2 years of age (possible liver failure)

- pain in the abdomen, upset stomach, vomiting, or loss of appetite (possible disease of the pancreas)

- easy bruising, nosebleed, other abnormal bleeding (problems with clotting)

Tell the doctor right away if you notice any of these problems, but don't stop using the Depakote unless the doctor says so.

I hope this give you a littlei info.

Take care,



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Veteran Member

Date Joined May 2007
Total Posts : 3715
   Posted 9/15/2009 12:31 PM (GMT -6)   

You might try your post over in the bipolar forum, as well. Lots of our members have been on depakote.

Co-Moderator, Bipolar Forum
Bipolar II

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