I take Calcium / Magnesium, Valerian Root and Melatonin. I suffer from Chronic Daily Migraines and find the Calcium / Magnesium and Valerian Root help control the pain and calm the anxiet that comes about from daily pain. The melatonin is helping me sleep. Right now I feel like I go three rounds with Mike Tyson each night. I take these in addition to my anti-depressant - Celexa.
I have taken St. John's Wort as well as an anti-depressant, though don't take it as well as an anti-depressant. It didn't have as strong effects as the Celexa.
I take 6 tablets of Calcium / Magnesium (350/175) - 2 in the morning, 2 at noon and 2 in the evening. I started at the recommendation of my naturopath and confirmed this with my doctor and he says this is fine.
I am taking 3 tablets of 3 mg of Melatonin nightly. I'm not experience any groggy feelings with it. I have checked this with my doctor as well and he says its fine, not addictive. I'm coming off pain killers so I'm not sleeping well at all, waking up at 3 am and not able to go back to sleep. I started the Melatonin and Valerian Root last week and am now sleeping well and waking up feeling good.
I also suffer from chronic daily migraines and take three medications daily for those so I was already used to taking a bunch of medications . I have a dispenser in which I put the pills each week and just take the little square full when I get up, at lunch and then in the evening.
I have found that I was tired this week so I am going to reduce the melatonin to 2 3mg tablets each day this week. I find a lot less side effects from natural remedies than medications.
Good luck! I'm intersted to hear how it goes.