I am currently on Remeron for depression and Klonopin for anxiety, but feel the Remeron is pooping out on me. I don't feel as good as I used to. I am thinking of going back on SAM-e (supplement) that I was on for awhile. I was on it for three years and depression free. I was wondering, if it would work again, if I went back on it. Was wondering if anyone has gone back on a medication that they used to be on and had it work again? I am a bit fearful of trying a new antidepressant and side effects. Thanks for reading.