Tricyclic antidepressants

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sooper
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   Posted 7/5/2006 4:34 PM (GMT -7)   
Anyone take these ?


I feel like such a feak taking a medication from the bloody 50's mad

But from what I read online they are generally as effective as the newer SSRI that came out in the 90's. It says these have more side effects, but so far I havnt noticed anything at all. But I only started on 50mg for a week, then 100mg for 2nd week then up to 150mg, im sure then I might see some side effects. I know when I first started paxil, I lost sex drive, had nausea, and woke up sweating like mad man. Effexor made me twitch, and couldnt get it up with celexa.
im a professional... on an amateur level !


zorna
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   Posted 7/5/2006 6:17 PM (GMT -7)   

 

Please keep track of any side effects.  Forget about feeling like a freak! If it brings about postive results thats the key.


els
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   Posted 7/6/2006 7:26 AM (GMT -7)   
I totally agree with zorna.  You need to keep in mind that though these meds are old they are tried and have been proven to be effective forms of treatment, or else they wouldnt still be in use and prescribed.  Alot of the doctors do go for the newer drugs at first but if the patient has problems on them then they go for the "old stand bys" which are the Tricyclic class of meds.  There isnt anything wrong with taking them, if they work for you....


 


sooper
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   Posted 7/6/2006 7:37 AM (GMT -7)   
I hope they start working soon. They are the same as SSRI and can take up to several weeks to kick in, though usually after two weeks most people notice improvements. Right before this I had been on 20mg paxil for two weeks, but I dont think that was much considering before I was on 40mg for a good bit of time. I start taking 100mg this evening of the imipramine. My grandmother is visiting my mothers, and boy she is just making more depressed, keeps asking about school, and talking about school, and I "dropped" out (I wanna get my head straight and finish my course, but at this rate it doesnt look good) She doesnt know I stopped the course, nor does she have any idea the reason im at my moms is cause I find it better to feel down and all weird out here Vs in town with my 5 random roomies. Though I have a cat, and I feel rotten leaving him there by him self, I drive in to feed him and change his liiter. Someone was like, "you shouldnt have a cat then" :( bah... I cant bring him here cause my mom has a really annoying agressive dog that puts the boots to cats.

If anything I seem to feel less "crazy" and more depressed, Im gonna try and start living back at my place tomorrow. My mom really doesnt understand, she is all about me pushing myself. I wish it was that easy. No matte rhow hard I push, it doesnt change my feelings.. thats the problem.
im a professional... on an amateur level !


els
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   Posted 7/6/2006 10:27 AM (GMT -7)   
I know its hard...especially when people give advice about something they have no experiance in or havent dealt with.  I'm sure your mother feels that she is being supportive of you and trying to help but it doesnt seem that she understands really how you feel and what your going through.  And unless she has experianced depression for herself it would be very hard for her to understand it.  It does sound as if your in a fustrating situation but do be sure that you dont isolate yourself from everyone who does care about your wellbeing and you.  You can always find support here...take care


 


Flavor flav!
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   Posted 7/7/2006 10:31 PM (GMT -7)   
Yah, tricyclics are way underated in terms of their effectiveness against depression and what not. They definetly have more side effects usually though. Imipramine helped my depression more than any other med by far, but after a year or so i eventually stopped it because i got sick of how sedated it made me.
Its just a matter of trying plenty of different meds. Dont think for a second that you will definetly find the right med for you within the first couple tries.Not that its not a possibility... but if you just stick with it, even through meds that turn out not to work for you, you'll eventually find one that greatly improves your psychological quality of life.

sooper
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   Posted 7/11/2006 7:36 AM (GMT -7)   
Glad to hear that you had relief from your depression. Im now on 4th day or so at up'd doesage of 100mg, still no side effects I can tell of, so been on this a week and a half I do feel tired off on and during the day, but nothing serious. I really hope this stuff gives me some motivation, it is just like I dont care about anything and will do anything to avoid everyone. I dont understand whats wrong. I hope it is depression, It feels more like im just insane. My rooms a mess, im home all the time, I wont answer calls from anyone. On the up side, I have managed to start getting through the days with out getting so frustrated about it all. Calmer about the situation, but still off from a decent mood. I dont really know why im so avoidant of everyone. I just wanna hide in my messy room. I think alot of it is simply cause im a party pooper, constantly down. Nothing to say. It is irony at its finest. I used to talk alot especially when I was younger. Now even the most simple convo with someone I really just dont find an interest to initiate a decent response. To me everything just seems blah, winding through my very boring days, i should clean my room, do some wash... go to the grocery store. Will pills malke me do this stuff ? everything just seems like so much work, even stuff that never used to, even things I enjoy like listening to music, when I was young and depressed I turned to music, now im like music ? I listen and I just wanna turn it off, the interest for everything is just nill... One of my favorite bands is coming and 3 years ago I would have been pumped up for something like this, now I dont even really feel like going. I never wanna do anything, go anywhere... im interesting, thats for sure.
im a professional... on an amateur level !


Flavor flav!
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   Posted 7/11/2006 4:13 PM (GMT -7)   
First off, what med are you taking? Second, what has initiated your depression? Death of a loved one? Adolescence? Knowing how old you are I guess would help as well.

While I took imipramine for a year or so and it helped my depression, it definetly made me feel extremely tired, and as what I saw mainly as a result of the sedated feeling; unmotivated to do much of anything or talk with anyone. Thats basically why I stopped. Im 21 and stopped the imipramine a few months ago and am now trialing on cymbalta. The only other meds I have tolerated for significant periods of times have been lexapro, and adderall. Ive tried just about every med ever made however.

Also, do you have mainly just a really sad, depressed mood all the time or do you have alot of anxiety of any kinds as well? I might be able to help direct you to a good med using my experiences if you detailed your situation alot more.

sooper
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   Posted 7/12/2006 12:57 PM (GMT -7)   
Hey there. Im not sure what made me depressed. Im hoping it was a lack of saratonin and norepinephrine... Im just on the imipramine right now. I have been so "depressed" for so long, I cant remember any route cause< but I . I think I started complaining of depression when I was about 17 or so. 26 in a month. I have always been a wierd kid, when I was young 7-22 I was very talkative, but it has slowed and these days, when people talk to me.. im just totally uninterested and unable to give any emotional response. people like me, im lucky there I guess, . but I serioulsy lack a personality I once had these days, especially face to face with people. I generally just seem to think everything sucks, and cant shake it. I dont enjoy things.... nothing really excites me, it is really creepy. I used to even when I was first depressed, I would use angry music, whatever, always something kept me going, kept me occupied, I looked forward to things evern though I wasnt the happiest guy.. that got me through life, plans, friends, activities . I used to go out with friends and dance. I loved to dance, something in me says I still do but something else fails to initiate enough desire to be bothered. I think really I just had a really twisted upbringing, I dont even know anymore. I like nothing much though :s I never had many hobbies. and even when I think of things that I used to like, as simple as listening to music, something is missing, I just wanna turn it off, and I just draw this wierd blank thought about why I dont wanna listen. I dont really feel super down. Though walking a kid told me to smile "life isnt that bad" and then I paid attention to this and I do have on a rather irratable depressed face alot of the time. Right now in life nothing drives me. The few things that drive me, I dont enjoy much, I feel like a freak cause I tell myself, wait a minute thats FUN! take out the emotion though, I just logically say this is a fun thing, but yet I dont wanna do it. then im just like meh. Im thinking with time it all gets better or I go crazy. I have been avoiding my friends. This bugs me alot. I almost felt like calling someone today. . . maybe the pills are starting to work. Bah Who knows. That kinda bugs me I need a pill, I just hope it can shake this. Sometimes I think im not depressed and I just have grown up really odd. But they tell me im depressed. It is tricky for me though cause paxil took me from depressed (hek if I could go back to that depression I sure would and not have takin anything, though I was depressed there was still a drive there to keep myself looking good and tanned, im a two faced wierdo add a lil tan and im the man - I used to go out on weekends, listen to music, and so on) paxil sent me manic though. The funny part is, is alot of people just let it all slide, I look back and says.. I was insane, ha. It is pretty embarassing to say the least. The funny thing is I knew I was manic, I didnt see it as a problem at the time and "enjoyed" the ride. Life is a big pile of poo sometimes. My goal tomorrow is to clean my room and get groceries. I have a real big social issue right now, I think its cause im such a mess, I just dont wanna deal with people especially since I am like zero personality. Im a freak :( I have a hard time making friends these days compared to when I was younger, i need better person to person communications skills or perhaps that ties in with my depression. This is long. I am so bloody bored.
im a professional... on an amateur level !


Flavor flav!
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Date Joined Jul 2006
Total Posts : 21
   Posted 7/14/2006 11:38 PM (GMT -7)   
Well, I could make this even more long and complex if I related all your thoughts to my life experiences, as they ARE pretty similiar, but i'll try and keep things simple, so forgive me if i sound overly frank. Feel free to ask me to expand, or do so yourself, on anything in particular though.

It sounds like youve allways had depression. You just have been motivated by the thoughts that you will eventually pull through if you just listen to some music or do whatever else helps you deal with those periods of deeper sadness (and it sounds like those strategies worked pretty well for you). I'd guess that at your age, its becoming more and more apparent to you that there really is something mentally 'off' with your mood (as in you find yourself depressed and apathetic more often than others). Its best described as a sink hole i guess: youve been able to avoid being dragged entirely under by keeping a positive attitude and doing things you enjoy to keep your spirits up. However now you have just really become fed up with clawing to avoid being dragged under by your depression and have started to give up (or given up, realizing that things are not as emotionally 'difficult' for others as they are for you most of the time; and sulking in that realization). OR, a massive amount of stresses has kind of just shoved you into the middle of the sinkhole and under, so to speak, which is not hard to imagine dealing with life at 26 years old.... I hope none of that comes across as condescending, the first part was exactly what I lived like, until eventually at 7 years old I got pile driven into the middle of the sink hole, so to speak, by a massive stressor.

Anyway, I had guessed you were taking imipramine from the changes in feelings you described, and I was right (toot, toot). ;)

Everyone reacts differently to different meds but a real common side effect of Imip is sedatedness. Like I said, imip helped with my depression in terms of 'worrying about things' but it also made me really lazy and made me want to avoid people because I just didnt feel like talking with anyone. I described it better in my other post.
Like I said, ive tried about everything made, I have been on paxil and had the same effects, depression was definetly better but I was pretty off the wall too.

In my unprofessional (but probably more qualified than most professionals) opinion I would suggest you try a medicine like effexor, lexapro, or the cymbalta med I mentioned I recently started taking. Tricyclics like imip are good at helping depression, but their side effects usually bring on a bunch of other issues like the ones i mentioned before.

As strange and ridiculous as it may sound to alot of people, a pill that helps balance your brain chemistry and therefore improves your depressive symptoms IS somewhat similiar to taking a tylenol that makes your headache go mostly away. However, finding the right med/combinations of meds is a helluva lot more complicated. I guarentee you there is a med/s out there that will help with what symptoms you describe. However, alot of newbies to psych meds get skiddish after they try a couple meds that are ineffective for their symptoms and say, "well I tried meds and they didnt work." They give up on meds entirely and even sometimes carry around a negative stereotype of all meds because they tried a few that made them feel messed up. Thats ignorance. Dont be one of those people, you'll just be doing a MAJOR disservice to yourself. Also, dont put up with a doctor that makes you stay on a med for months at a time that is ineffective for you or possibly even making things worse.
One last thing, when you do find a med that helps, you probably will think you can stop the med because your 'feeling better now'. Dont, you'll start feeling your symptoms again. The goal of psych meds isnt to 'take a break' from depression. It is to help balance your mood consistently. Smoke if you only want temporary relief. :)
 
 

Post Edited By Moderator (els) : 7/20/2006 12:50:03 PM (GMT-6)


canislupus
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   Posted 7/15/2006 3:11 AM (GMT -7)   
I used to be on Elavil and Siniquan at different times in my life and they were the most effective anti depressants I ever experienced.  My doctor would not even consider Elavil or Siniquan because in her words they were so OLD!.  She gave me Cymbalta instead and I hate it.  I feel like a hypet zombie.  I can not sleep at all.  I am not depressed but sleep is something other people do since I started taking Cymbalta.
 
If you are taking one of the old standby's consider yourself lucky dude.  I wish I could get my doctore to see the light.

sooper
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Date Joined May 2003
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   Posted 7/16/2006 7:34 AM (GMT -7)   
Thanks for the replies. Flav, I guess im lucky cause I dont feel totally sedated from the imip. I will stick with it for a month and see if it starts to relieve my symptoms at all, and if not jump on to something else. Cymbalta sounds good, I guess though it really is just hit or miss for each person and a drug. I read you have ADD. I have this as well. I do not currenlty take anything for it though. I do smoke.. probably too much, it has become some sort of a crutch for me, and I know this is not a good thing, im using it to "escape" from my problems, and it isnt even an escape really at all, it just creeps me by time. I dont know why im looking at the world in such a different light these days, but I hope my thoughts alter soon. I am sure your right that there will be something that will help get me feeling better. Today I just feel like life has beaten me. I think to myself, what is all this really ? then I think about death... no one is getting out of here alive. Most people dont ponder death much at all, but for me it is something I think about all the time, especially when im depressed. I worry right now that no pill will ever help me, that I have simply been beaten by life, I have been raised you could say to be the way I am today and no pill will change it... im really scared of how much time I consume thinking about how I feel, how off I feel, and so on, it seems the more I think these things the worse the problems get, and the more I am left to think about them. I dont know hwy I have gone into such a social withdrawal. Im gonna make myself hang around some people though tonight and hope it goes well and I can get my mind off these horrible thoughts.

How long have you been depressed for ? I hope the cymbalta works for ya.

Post Edited By Moderator (els) : 7/20/2006 12:51:48 PM (GMT-6)


sooper
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   Posted 7/16/2006 7:39 AM (GMT -7)   
canislupus said...
I used to be on Elavil and Siniquan at different times in my life and they were the most effective anti depressants I ever experienced. My doctor would not even consider Elavil or Siniquan because in her words they were so OLD!. She gave me Cymbalta instead and I hate it. I feel like a hypet zombie. I can not sleep at all. I am not depressed but sleep is something other people do since I started taking Cymbalta.


If you are taking one of the old standby's consider yourself lucky dude. I wish I could get my doctore to see the light.



Thats odd if it worked and your doctor doesnt wanna use it ! I guess side effects are a big problem with these older ones but I havnt had much problems so far. But it is just the start of week 3. Have taken full dose twice now. Had some headaches, slightly dry mouth, and there are periods where I do feel sedated, im gonna wait and see how I feel by friday. I have an appointment with the doctor a week after that, and if I dont feel better, or am having any side effects. I will move onto another med.
im a professional... on an amateur level !


Flavor flav!
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Date Joined Jul 2006
Total Posts : 21
   Posted 7/16/2006 7:03 PM (GMT -7)   
Yes, psych drugs really are hit or miss in terms of their positive/negative effects on people. While I hope imip starts to help you, ive never taken a med that I felt much different on whether I took it a week or for months. Again, everyone is different though.
I definetly would recommend something like lexapro for your concerns if imip turns out not to be cutting it.

I see you talking about being worried about if your doomed to your negative emotions and maybe no pill will help you... In my opinion if you havnt felt any improvement in terms of not feeling so negative that you still have those thoughts plagueing you (especially after a couple weeks on the med) than your not on a med thats helping your main issue very much. Just a thought. You wont quite understand what the hell im talking about until you do try a med that helps with this, as its pretty enlightening and quite amazing to suddenly not feel like crap all the time and suddenly have a pretty decent attitude (at least it was for me).

Flavor flav!
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Date Joined Jul 2006
Total Posts : 21
   Posted 7/20/2006 12:33 AM (GMT -7)   
I saw I forgot to answer your other question about how long ive been depressed.. I have pretty severe social anxiety disorder, generalized anx. disorder, ADD, and near clinical depression. While, due to genetics, im sure these issues would have come up later in life anyhow, what really set them off environmentally was my older brother being killed when I was 7, along with alot of other family issues.

The ONLY reason I have survived to this point has been for the love of my family and not wanting them to go through the pain we all went through before of losing a loved one.
However, the first time I got help from medication was an absolutely enlightening experience that I had been waiting my whole life for. I could actually just be myself, without beiing constantly buried under a mountain of my own negative emotions and anxieties. It put things into almost crystal clear perspective of how others were able to go about their lives everyday without becoming as overwhelmed and immensely frustrated as I usually found myself becoming.
I still have plenty of issues to deal with, depression and anxiety still being some of them, but medication has undoubtedly saved my life and made it well worth staying around for. Again, this being because meds simply help me to be myself, not because they turn me into another person in even the slightest way (which is something I feared greatly when first starting treatment). I'd love nothing more than to see all the people suffering from severe depression, anxiety, etc. experience the tremendous improvements in second to second quality of life that I have.
"I wish I could give you points for that grizzled exchange, but i cant."

Post Edited (Flavor flav!) : 7/20/2006 1:39:09 AM (GMT-6)


sooper
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   Posted 7/21/2006 3:41 PM (GMT -7)   
Depressed since you where 7. That really would suck to have something so bad happen at such a young age :( Im glad to hear that you have found some relief with medication. Im hoping to get the same results... It has been one week on the full dose of imip and my mood has slightly improved, though id still say im depressed. I whent out though to see some friends at least. Been hiding for awhile. Also the whole death issue is just a bad trip, im hoping it will pass sooner than later, ive been hung up on it before. But it hinders mood for sure more so now than in my past worries about it. Too much anxiety. I dont think this stuff does much for anxiety, but I have read some people are prescribed imip for anxiety. anyhoo ! hope your doing well today :) Do you take anything for ADD? I dont really see mine as a huge problem right now. Used to take dexedrin when I was younger but it made me a zombie. . . these days my hyper isnt much of a problem like it was when I was younger. But my attention span sucks
im a professional... on an amateur level !


Flavor flav!
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Date Joined Jul 2006
Total Posts : 21
   Posted 7/21/2006 6:44 PM (GMT -7)   
I take 5 mg of adderall a few times a day for add. Adderall also helps my depression massively and my anxiet., Anything over 5mg at a time and i get a little jittery and get more anxiety. Imip helped me massively with my depression, and while it helped with my anxiety in terms of being open to talking with people, it increased my physical anxiety symptoms tons. That might not make sense, but the brain is weird that way.

Ive found either my depressive, or anxiety symptoms ( i cant differentiate which is which because they are intermeshed so much of the time) have gone up greatly since i stopped the lexapro and started the cymbalta. My general anxiety and social anxiety are definetly improved (as in lowered) however. Ugh, if only i could take both at once id be taken care of for once in my life... darn it. Never been this close before to having a handle on my depression/anxiety. Thats progress in itself however. Anyway, good to hear from you, this forum is too inactive. Take care.
"I wish I could give you points for that grizzled exchange, but i cant."


sooper
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   Posted 7/22/2006 7:04 AM (GMT -7)   
Flav - It is a slow web board. I also have crohn's, and that is the most active form on the site if you look at the stats on the main page, I dont post or even look in there much at all though these days, im too lazy and uninterested. Maybe it is part of the depression.

It is too bad you cant take the two meds together. But if you find the lexapro and cymbalta would do it, perhaps there is a different SSRI you can try with the cymbalta? just a thought. At times it can all feel so helpless, like your never gonna have a steady decent mood.

What do you mean by physical symptoms? Like a fast heart beat ? I havnt had many side effects from the imip but I have been sweating a lil at night. I would say there is a good chance I might go for something else when I see the doctor next week. I started at 50 for a week then 100 for a week then 150. It will have been just about a month next friday and I havnt seen any great improvment in depression, but I do feel more relaxed in the mornings where as before I was really weird for the first part of the day, thought I was losing it. I hope that doesnt come up again if/when I change meds.
im a professional... on an amateur level !


Flavor flav!
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Date Joined Jul 2006
Total Posts : 21
   Posted 7/22/2006 2:32 PM (GMT -7)   
I took 25 mg of imip at most and it made me feel incredibly drunk, dizzy and just sedated as hell. Its amazing you can take so much more without feeling it much. It helped my depression tons though like i said, mainly I noticed that I laughed alot and had a higher mood all the time.
What i mean by physical symptoms of anxiety is general tightness of the neck and muscles, being nervous about looking people in the eyes due to the sudden rush of a panic attack that might come on if I saw they were giving me a weird look or something like that. Being extremely nervous that i wouldnt know what to say or have a response which usually gives me a sudden panic attack of sorts. More social anxiety stuff that I have that you may not experience.

My brother and sister have issues with just depression mainly and they have had great success with effexor, and I think cymbalta is a newer type of effexor, i could be wrong. You might give that a shot next if you decide to quit the imip or add a new med. The cool thing about imip is its so darn cheap.
"I wish I could give you points for that grizzled exchange, but i cant."

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