Is anyone taking 2 antidepressants together?

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tangerine bear
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Date Joined Aug 2005
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   Posted 10/11/2006 3:34 PM (GMT -6)   
Hi, confused
 
I just got back from the doctor's office. I (of course) have clinical depression, which we have been treating with Lexpro (currently 15mg) for a little over a year and a half. My doc wants me to add Wellbutrin XL150. I've had a recent "depressed episode" which is why she wants me to try adding something else. I'm REALLY nervous about this... is anyone else on this combination of meds? I don't know what to expect. She was very adamant that I take the Wellbutrin in the a.m. (I have always taken the Lexapro at night). Any feedback from others would be very helpful. Thank you!
 
Bear
It's a jungle out there.....
 
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judyinky
Regular Member


Date Joined Aug 2006
Total Posts : 254
   Posted 10/11/2006 7:03 PM (GMT -6)   

Hi Bear,

I dont' think that it is unusual for the doctor to mix anti-depressant medicaton.  One may pick up where the other let's off, and I'm sure your doctor has her reasons. But, there is nothing wrong with you questioning what she is doing . You might want to check out some websites if you can find any about this.  You might find some information on remedyfind.com. I use it a lot to check out a lot of medical and prescription questions.

I hope this helped.

Judy


"Hope is seldom found in the things we can see;it is the sweet fragrance of grace."

             

 




wmnak
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Date Joined Jul 2006
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   Posted 10/11/2006 11:28 PM (GMT -6)   
Schizoaffective/Bipolar husband has been on Lithium for several years.  Psychiatrist added Wellbutrin XR just a couple of weeks ago and there has been a noticeable, positive, change. I've no idea how Wellbutrin would interact with Lexapro ... check it out online and closely monitor your feelings.
Let us know if/how it is working for you.  :-)

tangerine bear
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Date Joined Aug 2005
Total Posts : 941
   Posted 10/12/2006 9:12 AM (GMT -6)   
confused  Well, I debated with myself all morning.... should I take the Wellbutrin? I won't.. I will...So finally the "I'll mind the doctor" won out. I took the pill about a half hour ago, and I'm waiting to see what horrible thing will happen next. Hopefully, nothing, but I still think that I'm taking too much medicine. sad It seems that I'm stable, MOST of the time, and then I have these "relapse" times, when my depression comes back. Does that warrant adding another medication ALL the time? I have no clue. I sure don't want to be a walking ZOMBIE, as it is, I have difficulty crying many times, just from taking the one antidepressant. Oh well, sometimes I suppose you have to trust a doctor and hope they are right. I had called my therapist yesterday when I got home, and she pointed out that she was NOT an MD, but none of her patients are on this combination, and said it might be best to see the psychiatrist at her office for a second opinion, but I wouldn't be able to see him for another week... Soooooooo, I just popped the pill. I sure hope this isn't a mistake. Reading the possible side effects of combining with other antidepressants online sure isn't such a good plan... now I'm waiting for the worst to happen. I'm really praying I'll be ok, especially considering that I'm home by myself...
 
Bear confused

It's a jungle out there.....
 
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tase2
Regular Member


Date Joined Aug 2006
Total Posts : 65
   Posted 10/12/2006 1:56 PM (GMT -6)   
I have been on 2 meds at once for at least 5 years. I have been taking Wellbutrin and Effexor the whole time. We have played around with dosage amounts. I am currently taking 75 mg Effexor and 450 mg Wellbutrin. I do not feel like a zombie, although I do get tired.

I think taking 2 or 3 meds at once is a fairly common occurance and I urge you to give it a try. Also try to stick with it for a few weeks (if you can tollerate it) to let your body adjust before making any final decisions.

It might also interest you to know that my wifes current combo is Lexapro 15 mg and Wellbutrin 450 mg. She was just upped to the 15 mg and seems to be doing fine.

Good Luck

tase

Puddin_
Regular Member


Date Joined Sep 2006
Total Posts : 20
   Posted 10/12/2006 9:22 PM (GMT -6)   
Hi Bear,
 
I am taking two antidepressants ... 80 mg of Prozac and 300 mg of Wellbutrin.  I've been on the two since April, and so far so good .. although I'm finding that I'm at a plateau.  The Wellbutrin was added to compliment the Prozac to give it a boost.  It worked for a bit .. but have recently had a depressive episode about 3 weeks ago.  I'm hoping at my next appointment something can be done, because the tears are still flowing. 
 
I hope you do well on the medication. 
 
Hugs,
Puddin (Sharon)
~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
 
Diagnosed: OCD, Anxiety/Panic Disorder, Social Phobia, Chronic Depression, Eating Disorder, Hypothyroidism, Fibromyalgia, Costochondritis, Restless Leg Syndrome, Chronic Fatigue Syndrome
 
Current Meds: Prozac, Wellbutrin, Synthroid, Furosemide, Meloxicam, Pantoloc, Spironolactone, Clonazapam


tangerine bear
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Date Joined Aug 2005
Total Posts : 941
   Posted 10/12/2006 10:33 PM (GMT -6)   
Thank you all so much for your kind replies. I am not so sure what I am going to do. I have been SO hyper all day. I feel like I drank a whole pot of coffee. I have even taken my evening dose of xanax, and I'm not in the least sleepy. I'm not so sure I can tolerate this feeling... not only jittery, but my head has strange sensations, and I'm having some pain in my chest. I'm thinking about NOT taking it again in the morning. It's amazing that such a tiny little pill can have such a strong effect!!!! Oh well, thanks for listening to me vent.. (((Hugs to all))).
 
Bear
It's a jungle out there.....
 
Theme song from "Monk" by Randy Newman
 
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slowlygoingcrazy
Regular Member


Date Joined Sep 2006
Total Posts : 122
   Posted 10/12/2006 11:44 PM (GMT -6)   
I know the feeling of being overmedicated. I'm on only one but I'm taking 225mg of EffexorXR which apparently is the highest recommended dosage. Not exactly appealing to know I'm all the way at the top. My doctor doesn't want to add another anti-depressant but he has given me tryptan to try to increase the effectiveness of the EffexorXR. Still haven't managed to give it a try yet due to a few paper work problems but hopefully I'll get those sorted out soon and I can see if it'll help at all. Don't like the idea of more meds but even the 225 mg of EffexorXR has little effect, well, it's probably doing more than I realize, but I still feel horrible most days. In fact here I am again still up at nearly 2am.... I really didn't want to do this tonight but it just happens... It's hard to stop and when the typing and clicking is soothing to the soul in the sense I feel like it's keeping the craziness in check, it makes it even harder to stop. Anyways, the fingers are sore, the eyes are heavy, and so is the heart, but it's time for bed. Keep us posted on your progress. Sometimes the first week can be the roughest. I know I found the initial period of the EffexorXR tough, and each increase, had it's few days of adjustment, but once I adjusted it was fine, of course, I can't forget a dosage anymore either because wow, the withdrawal symptoms can hit fast and furious.... Had that yesterday, but my son's birthday kept my mind busy with other things and it was a really great day. In fact I found the social time so uplifting last night I finally joined an online group for meeting people. So I'll see what happens.... Anyways, I hope things are better. Sorry about the rambling on here. It happens! It helps. And that's why Healing Well is here, so vent all you want and don't apologize. We all do it!!!! And we do it because we have to or we'd all go completely insane!!!!
 It would be easier to tell people I have cancer than it is to tell them I am severely depressed.....


tangerine bear
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Date Joined Aug 2005
Total Posts : 941
   Posted 10/13/2006 12:01 AM (GMT -6)   
Hi Slowly,

I can really feel empathy for the things you have said. I have had a diffiuclt time with my medicine as well. I know my doctor wants to try to get me stable, but it seems that as soon as I start getting a bit too much of that good old seratonin in my system my body just goes crazy. When I tried to go up to 20mg of the Lexapro, my legs actually started giving out from under me. I could tolerate the twitching, but the leg pain was just unbearable. This insomnia is just unbelievable to me. If I go through with this Wellbutrin idea, I am sure that I will need to add a sleeping pill. This is just more than one person can take. I know what you mean by the comfort of the typing... it does seem to help. I'm really not sure I can make it through a week of this, or even one more day. I'm definitely calling the doc tomorrow, I don't think this was what she had in mind to help me improve.

(((Hugs))),
Bear
It's a jungle out there.....
 
Theme song from "Monk" by Randy Newman
 
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Cathi
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Date Joined Jul 2003
Total Posts : 702
   Posted 10/13/2006 2:16 AM (GMT -6)   
Bear..

I am from the Breast Cancer board...I hope you dont mind my responding.
I have been taking Lexapro and Wellbutrin together for the past 2 years.
I have had no problems taking both and it really seems to help...
Good luck on whatever you decide to do..

Cathi
Sometimes it is a slender thread, Sometimes a strong,
stout rope; She clings to one end, I the other;
She calls it friendship; I call it hope....


bluemeanies
Veteran Member


Date Joined Jun 2004
Total Posts : 1372
   Posted 10/13/2006 7:06 AM (GMT -6)   
I am taking Celexa and Remeron together and the combination is helping. I hope it works for you too.

hopefulmigrainer
Veteran Member


Date Joined Oct 2006
Total Posts : 902
   Posted 10/15/2006 12:56 AM (GMT -6)   
Dear Bear,
 
I was on Cymbalta for a long time which was working great until I had a crises.  I went into a major depressive episode and needed to go to a psychiatrist instead of MD.  She switched me to Lexapro and we had to try different things at first.  She wouldn't prescribe xanax.  She kept giving me samples of meds that you give bipolars that are in an acute manic phase.  I could not tolerate those and she gave me Trazadone for sleep but I was allergic to it.  I didn't get better on the Lexapro so she added the Wellbutrin and it helps SIGNIFICANTLY.  I now take 150mg. Wellbutrin in the morning and 5mg. Lexapro in the evening.  I do sympathize with how you feel about meds.  I hate taking pills.  Do you have any physical health problems?  You should read the migraine forum.  Nearly all of us have to take these powerful brain/nerve drugs that have horrible side effects and nearly all of us suffer depression too.  Hang in there until you find the right medicine and don't forget to do all of the other important things too - like caring for yourself, whatever that is for you.  Do it as often as you can.
 
Blessings,
K.

immunosci
Regular Member


Date Joined Jun 2006
Total Posts : 326
   Posted 10/18/2006 2:23 PM (GMT -6)   
Hi, Bear. I'm from the Crohn's Disease forum, but have suffered with depression for as long as I can remember. I spiraled into a major episode after my mother passed away last year. My doctor increased my Lexapro dose to the maximum, but that wasn't enough. She added Wellbutrin to it. She said that Wellbutrin is an "activating" type of anti-depressant, so it enhances the effects of the other one. It helped greatly for a while. Unfortunately, I had the worst episode of depression I've ever experienced - almost hospitalized. I've been switched to Cymbalta in addition to the Wellbutrin with Trazadone added on to help with sleep. It's the best combination I've ever been on. I did have a lot of nausea and some hyperness/agitation with the Cymbalta in the beginning, but it settled after a couple of weeks. I hope you find a combination that works for you.

Jen
-Formal diagnosis of CD in terminal ileum in July 2005.
-Experienced what were most likely small flares for 12-15 ys.
-6-MP, protonix, cymbalta, wellbutrin, trazadone, metamucil capsules, allegra, nasonex.


Nicky (coquitlam55)
Veteran Member


Date Joined Jul 2005
Total Posts : 505
   Posted 10/20/2006 12:37 PM (GMT -6)   

Hi tangerine bear,

My mom's doctor prescribed Wellbutrin and Celexa for her. She tried it for a while but didn't like the feeling and went back to Celexa.

Nicky

Hi slowlygoingcrazy,

I took EffexorXR for six months and found it didn't work at all compared to Celexa. I tried taking the maximum dosage and it made me feel really weird. I didn't actually realize it wasn't working it was my family and psychologist. I was getting really upset at minor things and felt my life was totally out of control. Finally when my doctor said, "you know I don't think Effexor is working." I bit the bullet and switched. It's four months since the switch and I feel much better now.


Nicky
 
"Yesterday is history. Tomorrow is a mystery. Today is a gift. That's why its called the present."
I'm working everyday to overcome the pain and depression that comes from my chronic migraines.

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