Antidepressants working for a few days then stop working?

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shift
Regular Member


Date Joined Nov 2005
Total Posts : 242
   Posted 4/6/2007 10:53 PM (GMT -7)   

I suffer from treatment resistant depression. I have been on several antidepressants, antipychotics (Zyprexa) and lamotrigine. After only a few days, each one of these medications will work for me and I will be 100% better but this will only last a few days and then they stop working and my brutal depression comes back and they never work again. Has anyone experienced this and/or does anyone have some advice for this.

 

Thanks Shift


jordaNZone
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Date Joined Sep 2006
Total Posts : 752
   Posted 4/6/2007 11:37 PM (GMT -7)   
Hi shift..well, in my own experience antidepressants take 6 to 8 weeks to fully work..not sure about your other meds you mention..the only quick relief pills I have taken are like valium based ones for anxiety...
The thing is that you cannot only rely on the meds to work..you have to work hard too at getting yourself together..have you tryed counselling/therapy in conjuction with meds?
I understand that meds are not for some people...need more info really so we can help if possible.
Keep posting.
Maree
Forum Moderator - Depression
Forum Moderator - Anxiety-Panic Disorders
 
"In any moment of decision,
the best thing you can do is the right thing,
the next best thing is the wrong thing,
and the worst thing you can do is nothing."
Roosevelt.
 
Friends are quiet angels who lift us to our feet when our wings have trouble remembering how to fly. 
 


shift
Regular Member


Date Joined Nov 2005
Total Posts : 242
   Posted 4/7/2007 12:06 AM (GMT -7)   
Thanks for the responses Maree. My diagnosis is agitated treatment resistant Major Depression. I stay on each medication I try for over two months with no response; However my brutal depression, (literally like a switch coming on) goes completely away after a few days on the medication and lasts for a few days; at which time the switch goes off and I am back in the pain and darkness and the switch never comes back on. There is no way this is a placebo response. It is to profound a change and has not happened with all medications. Would love any advice.
shift

jordaNZone
Veteran Member


Date Joined Sep 2006
Total Posts : 752
   Posted 4/7/2007 12:50 AM (GMT -7)   
Hi shift..I have just typed in "agitated treatment resistant Major Depression" as a google search..and it came up with several websites which may be of interest and/or helpful to you...
Worth a try anyhow :-)
Maree
Forum Moderator - Depression
Forum Moderator - Anxiety-Panic Disorders
 
"In any moment of decision,
the best thing you can do is the right thing,
the next best thing is the wrong thing,
and the worst thing you can do is nothing."
Roosevelt.
 
Friends are quiet angels who lift us to our feet when our wings have trouble remembering how to fly. 
 


ShynSassy
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Date Joined Dec 2005
Total Posts : 3036
   Posted 4/7/2007 5:25 AM (GMT -7)   
Shift,
I agree with Jordan you can not rely solely on meds. You have to sit down and figure out what sparked your depression and try to heal from that.
I also got very frustrated with taking meds at first because I wanted a quick feel better pill. Valium and Prozac did that,but I was walking around like a zombie and did not deal with what was going on mentally.
Healing is a long road,and counseling and meds can be a good combo when you continue with a strict treatment.

Stay strong and keep us posted

Shy
Mod- Depression

Chronic Depression, Panic Attacks,Anxiety Attacks,Anorexia

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"I am woman,hear me roar one day and cry the next!!!"


shift
Regular Member


Date Joined Nov 2005
Total Posts : 242
   Posted 4/7/2007 8:47 AM (GMT -7)   
Thanks for the help.

els
Veteran Member


Date Joined Oct 2005
Total Posts : 4031
   Posted 4/8/2007 7:44 AM (GMT -7)   
Hi Shift,  Actually there is a gene in the body that causes some people to be treatment resistant to antidepressants/antipsychostic medication.  It is very important that your doctor or hopefully the physician that is treating you is a psychiatrist is knowledgeable regarding these matters.  Here is the link on this... http://www.nih.gov/news/pr/dec2004/nimh-14.htm
 
Here is an article on stratgies for medication management for those who are treatment resistant.  It doesnt really relate to the gene factor but what I am posting here is trying to tell you not to give up hope here.  There are people who have this very same problem and are able to find the right treatment.  Please keep posting and letting us know how your doing. http://www.aafp.org/afp/981200ap/cadieux.html
 
 

Elisha
Co~Mod: Depression
Moderator: Heart & Cardiovascular Disease
http://www.healingwell.com/donate


shift
Regular Member


Date Joined Nov 2005
Total Posts : 242
   Posted 4/8/2007 10:11 PM (GMT -7)   
Thanks Elisha that is helpful.

Shift

djdaz_1985
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Date Joined Jan 2006
Total Posts : 2408
   Posted 4/9/2007 3:45 AM (GMT -7)   

Hi there,

As far as I am aware anti-depressants take some time to 'kick-in'. My doctor told me it woul be 4-6 weeks, but this could be different for different meeds and different people. The feeling you get initally (Where you feel great) could simply be expectation. You have something that you have been told will make you better and because you expect it to, it does but the feeling only lasts for a short period of time so potentially, this is what you are describing. As for treatment, I believe that meds are simply a coping mechanism for depression. For some people it allows them to cope to the point where they feel they are able to deal with the root cause by themselves (Hence, the drug can be seem as the 'cure') but for others, they need that little bit of extra help in the form of 'talking medicine' (I cant remember where I heard that phrase but I think its great! tongue   If you are resistant to meds then I would definately look into talking medicine either in the form of self-help or professional counselling.

I hope this helps

Darren


Everyone has a guardian angel. They help pick you up when you fall, comfort you through your times of need and help you appreciate the times when things are going well.


els
Veteran Member


Date Joined Oct 2005
Total Posts : 4031
   Posted 4/12/2007 9:19 AM (GMT -7)   
Shift, you are most welcome for the information :-)
 
djdaz 1985 said...As far as I am aware anti-depressants take some time to 'kick-in'. My doctor told me it woul be 4-6 weeks, but this could be different for different meeds and different people. The feeling you get initally (Where you feel great) could simply be expectation. You have something that you have been told will make you better and because you expect it to, it does but the feeling only lasts for a short period of time so potentially, this is what you are describing. As for treatment, I believe that meds are simply a coping mechanism for depression. For some people it allows them to cope to the point where they feel they are able to deal with the root cause by themselves
 
Darren, you are correct in the fact that antidepressant normally take 4-6 weeks to reach their effective level in a persons body.  This always does depend on the person though.  I would however disagree that medication (antidepressants) are a coping mechanism for depression.  Depression in a lot of people is a chemical inbalance of serotinin in their brain...this is an actual medical condition and cannot be helped.  Antidepressants restore the levels of serotinin, which is not something that a person with depression can just do on there own.  Depression isnt something that we cause to ourselves.  Here is a link from the National Institute of Mental Health on Depression so maybe you can become more knowledgeable on this subject.  http://www.nimh.nih.gov/HealthInformation/Depressionmenu.cfm

Elisha
Co~Mod: Depression
Moderator: Heart & Cardiovascular Disease
http://www.healingwell.com/donate

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