I have to weigh in on this one..........I was taking Vicodin for pain and it reacted with my AD's something awful. My blood levels on my AD's were off the charts. I was seriously ill combining the 2. I am now on cymbalta for depression not pain and I do not take any narcotic. I live with the pain but I can as mine is controlled with OTC NSAIDS.
My experience was very bad mixing the 2 meds so please be careful.