I just did a quick search on Alpha Lipoic Acid and found this:
Side effects of alpha lipoic acid may include headache, tingling or a "pins and needles" sensation, skin rash, or muscle cramps.
There have been a few reports in Japan of a rare condition called insulin autoimmune syndrome in people using alpha lipoic acid. The condition causes hypoglycemia and antibodies directed against the body's own insulin without previous insulin therapy.
The safety of alpha lipoic acid in pregnant or nursing women, children, or people with kidney or liver disease is unknown.
Not sure if this may be affecting anything but it is interesting.