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Regular Member

Date Joined Nov 2009
Total Posts : 43
   Posted 12/14/2009 12:19 PM (GMT -6)   
Hello to everyone in this forum. I am a newer member to Healing Well and have been posting almost exclusively in the Ulcerative Colitis forum.

I have been a Type II diabetic for 10 years and only in the last 5 have started taking Metformin. I started with on 500MG ER/day and in the last few years up to 2/day.

For almost one year I have been experiencing my first UC flare up and am now on Prednisone, which has shot my BGL through the roof (post meals in the high 300's).

My doctor took me off of the Metformin because of the toll it can take on the GI tract and because he did not think it would help while my sugars are this high.

So, he put me on PRANDIN. I have been taking 3-10mg pills before each meal and it has brought my fasting levels to normal but my post meal readings are still in the 200's. I'd like to hear from other PRANDIN users to see what your experience has been.

Thank you,

Veteran Member

Date Joined May 2006
Total Posts : 547
   Posted 12/16/2009 7:46 PM (GMT -6)   
G'Day & welcome!

Would you consider insulin? Just a suggestion before I ask what your diet is like :-)

It may be a way to see your BGL levels into some sort of 'normal' zone without the dozens of side-effects drugs can have. Insulin is a hormone not a drug. It doesn't cause any number of chemical reactions (side-effects) that drugs do. It supplements what your body already makes. Just something to consider.

Prednisone is a wonderful and powerful drug but it's side effects can be disastrous for diabetics; high blood sugar is almost to be expected. High 300's is most definitely too high, even for someone on Pred. Gotta get that down somehow; it's causing damage..

Not familiar with Prandin but, from what I read, it seems to cause one's pancreas to produce insulin quickly so as to have it present in the blood by the time the food hits the stomach. Sounds to me like the pancreas would take a beating if on this drug for any length of time (just my opinion). One of the things it doesn't seem to do that Metformin did was handle any insulin resistance (IR) issues you might have. Met makes the pancreas produce more insulin, too, but it also helps the resistant cells that need the insulin to "take it up" so to speak. Met seems more like a background/ long-term approach, while Prandin seems like, well, like an oral insulin shot :-)

One of the hardest and best things you can do for yourself with both diabetes and UC is to establish a regular diet. Do you have a regimen? What you eat can make a huge difference in BGLs.
- Phishbowl (Type 1 since Jan'05 - Levemir, NovoRapid)
"What's Not Measured Is Not Managed"

"It is impossible for a man to learn what he thinks he already knows"-Epictetus

Veteran Member

Date Joined Apr 2004
Total Posts : 6056
   Posted 12/16/2009 8:22 PM (GMT -6)   
You got super advice from Phish and if I might add something, could you start keeping a food diary and 2 hr PP record? That way you can pinpoint the worst offenders and maybe exclude them from your food plan. For me the example would be potatoes vs. rice. Small potato makes hardly a ripple. Rice, on the other hand, I might as well eat candy! Pasta is the same and corn as well. Barley, oatmeal and rye cereal are ok. Everyone is different and this small change may help you.

Good luck with this.
~ Jeannie, Forum Moderator/Diabetes & Fibromyalgia
I know God will not give me anything I can't handle. I just wish that He didn't trust me so much. ~Mother Teresa

"People are like stained glass windows: They sparkle and shine when the sun's out, but when the darkness sets in, their true beauty is revealed only if there is light within."- Elizabeth Kubler-Ross

Regular Member

Date Joined Nov 2009
Total Posts : 43
   Posted 12/17/2009 10:20 PM (GMT -6)   
Thanks to both of you for your insights. I have had diabetes for 10 years and so have had plenty of time to tweak my diet/exorcise/medication regimen. I started keeping a diary for my UC and it helps for my diabetes as well. My usual A1C hovers around 6.0, when all is well. My hope is that this is all temporary until I can get out of the UC flare I am in.

I have already seen my BGL's come down as I have reduced the PREDNISONE. I think my doctor prescribed the PRANDIN just for now, to get the BGL under control. I was mostly curious to hear if others take this medication, and it does not seem like many people do.

Thanks again,
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