Some Question about T2 and Byetta?

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Jasp
New Member


Date Joined Dec 2009
Total Posts : 6
   Posted 12/20/2009 11:25 AM (GMT -7)   
Hi Everyone,

I have some questions and no matter how hard I try I can't seem to find the answers. A bit about me. I'm 47 female and I have hypothyroidism (subclinical) meaning it's not my thyroid but probably in the Loop. Since 2003 I have been on medicine for the thyroid and it hasn't been an easy ride. During this time I was put on Cortef 20 mgs a day for adrenals and remained on this for almost 2 yrs in 2005. The last 8 months of the 2 yrs we were tapering my dose to wean down and come off of it. This also was not easy but I managed to accomplish this.

I have since been off of it for over 2 yrs but in that time I had gained about 50 lbs and my glucose was steadily raising. My AM fastings would be anywhere from 116 to 143 lab ranges were 65-99. This went on for over 2 yrs. When I questioned the Doctor he told me once off the steroids the glucose would go back to normal. Well that did not happen. Then I was told once my thyroid meds were at the proper dose and I became stable the glucose would go back to normal. This also did not happen. I pushed to be put on metformin and we finally did this and I have been on this now for 2 yrs adjusting doses and finally going to the long acting. I was on 2000 mgs a day and my A1c was 6.3 nothing I did would bring this back down. I changed doctors and knew the last thing to do was to get this weight off but no matter what I did this would not budge. He finally put me on Phentermine in June and to date I have dropped 52 lbs. I take 2 grains of Armour w/ 25 mcg's of levoxyl and after 7 years I have been at a good mixture and dose and have been steady for the last 4 months. This is fantastic for me. Since my glucose would not go below 6 even on 2000 mgs of Metformin XR I asked about Byetta and the doctor agreed to try this. I am on 5 mgs 2 x's a day and for the first time in 4 years my A1c was 5.9 after just 3 weeks on the Byetta. I'm hoping that the next labs in 3 months will show an even better number. My labs this time have been perfect. I couldn't ask for better numbers and haven't had labs this good in 7 yrs.

Here are some of my questions:

With the byetta pen do you have to throw out the pen after 30 days even if there is some left in it? The reason I ask is there are some times that I have not taken the shot because I wasn't able to eat or I was nausea and couldn't eat.

Somewhere I read that the shot has to be taken at least 6 hrs apart and that you can't eat within 3 hrs of taking the shot but now I can't find that info. Is this true? Do I have to wait 3 hrs after I eat in order to take the next dose?

Why do you get nausea some times but not others when taking the shot? Has anyone figured this out? I was told to take the shot and eat right away to avoid becoming sick but even with doing this I still will have the nausea sometimes.

My GTT was as follows:

Fasting 115 65-99
1 hr 230
2 hr 179

I had been on metformin long acting and was told to just not take the morning dose but wouldn't I still have metformin is my system if I'm taking a long acting form and dealing with the half life?

Is there still a chance that my glucose will return to normal and I will be able to come off of the medication? The lowest reading I have gotten has been 97 one time (fasting)

Why if you haven't eaten a thing all day will your fasting glucose be high like 143?

Thank you in advance for your time to explain some of the questions to me.
Jasp

Jeannie143
Veteran Member


Date Joined Apr 2004
Total Posts : 6056
   Posted 12/20/2009 9:15 PM (GMT -7)   
I don't use Byetta but I want to welcome you. We have others here on the pen and they should be along soon to help out but we're all extra busy this time of year and may not get on to post. Take care.
~ Jeannie, Forum Moderator/Diabetes & Fibromyalgia
I know God will not give me anything I can't handle. I just wish that He didn't trust me so much. ~Mother Teresa

"People are like stained glass windows: They sparkle and shine when the sun's out, but when the darkness sets in, their true beauty is revealed only if there is light within."- Elizabeth Kubler-Ross


Jasp
New Member


Date Joined Dec 2009
Total Posts : 6
   Posted 12/21/2009 12:53 PM (GMT -7)   
Thank you, I guess I will wait for someone to come along to help me out.

tjbessey
Regular Member


Date Joined Feb 2009
Total Posts : 65
   Posted 12/23/2009 8:06 PM (GMT -7)   
From the Top
 
With the byetta pen do you have to throw out the pen after 30 days even if there is some left in it? The reason I ask is there are some times that I have not taken the shot because I wasn't able to eat or I was nausea and couldn't eat.
 
Use the whole thing if you only go over by a few days you are fine.

Somewhere I read that the shot has to be taken at least 6 hrs apart and that you can't eat within 3 hrs of taking the shot but now I can't find that info. Is this true? Do I have to wait 3 hrs after I eat in order to take the next dose?
The drug is designed to be taken with two large meals in the day that are six or more hours apart. I take mine with breakfast and dinner. You can eat at any time, but keep in mind that Byetta changes the way your stomach empties and over eating will give your nausea.

Why do you get nausea some times but not others when taking the shot? Has anyone figured this out? I was told to take the shot and eat right away to avoid becoming sick but even with doing this I still will have the nausea sometimes.
 
My experience shows that over eating is the largest factor for people getting sick. Byetta changes the way your stomach empties (slows the process) this making you feel full faster. Also different carbs react differently for different diabetics with different meds. Diabetes is a very personal disease. What makes you sick does not make me sick. I would play around with the types of carbs you are eating, cut back on fats and reduce your portions.

My GTT was as follows:

Fasting 115 65-99
1 hr 230
2 hr 179

I had been on metformin long acting and was told to just not take the morning dose but wouldn't I still have metformin is my system if I'm taking a long acting form and dealing with the half life?
You need to take the long acting Metformin all the time. If that dose is to high then you script should be changes so that you are taking a smaller dose twice a day.

Is there still a chance that my glucose will return to normal and I will be able to come off of the medication? The lowest reading I have gotten has been 97 one time (fasting)
 
It depends in most cases I would say not. Unless you have a lot of weight to lose or you plan on making a change to a vegitarian lifestyle and even then no garantees.

Why if you haven't eaten a thing all day will your fasting glucose be high like 143?
 
You MUST eat regular meals as a diabetic. Bad eating habits are one of main reasons that people get this disease. Your body stores sugar in the liver. When you blood glucose gets to low you liver converts that sugar out of storage mode and into the bloodstream. It is a survival mechanism. Byetta effects three things in your body. The shot stimulates the production of insulin from the pancreas, is slows the rates at which the food empties and it slows the rate at which the liver converts those sugars into the bloodstream. You need to eat three square meals a day and have to health snacks in the middle.
I wish you luck in your journey.
 
tjbessey
byetta user

Jasp
New Member


Date Joined Dec 2009
Total Posts : 6
   Posted 12/23/2009 8:51 PM (GMT -7)   
Thank you so much for your time with answering my questions. I had lost 52 lbs and now have a healthy BMI and truly thought with the weight lost that my glucose would return to normal. My Glucose went out of control or at least normal when I started the steroids. I had been off of the steroids now for two years (I took them for two years) I then tackled the weight lost and got that under control. My Glucose seems like it's crazy glued to a number and won't no matter what go lower.

I take 1000 mgs of Metformin XR 2 x's a day. Even though it's long acting the doctor had me split the dose.

The reason I asked about the 3 hrs was a couple of times I had been so busy that I didn't eat. When I realized that I needed something it was within 3 hrs till dinner. I was told that not only could I not eat prior to the taking the shot so it got a bit hard. I would miss a meal then because I was going to eat within 3 hrs I was told I could not have anything in my stomach prior to the shot. I would wait for dinner time take the shot then eat something but I would get the nausea. Is it dangerous to take the Byetta with food in your stomach?

Has this helped you? Do you also take Metformin? Would I be able to give up the Metformin and only take the Byetta? Sorry for so many questions. It has taken me years to feel great with the thyroid I now feel like I got thrown a curve ball.

Thank you,

tjbessey
Regular Member


Date Joined Feb 2009
Total Posts : 65
   Posted 12/24/2009 7:24 AM (GMT -7)   
I normally I have snack at 3 pm and I eat between 6 and 7 every night. On two of three occasions I have started to eat and realized that I have not taken my shot or other meds. At that point I have just taken the medicine and continues on with dinner. I would not do this all the time, but it seems to be okay occasionally. Remember the major reason for the shot before a meal is the boost in insulin production prior to eating.

I take 1000 mg of metformin two times a day and 5mcg of Byetta. In all honesty I know just from how my blood glucoses have reacted that I will always need medication. My last three A1Cs were 6.0 Nov, 5.8 Aug, and 6.4 in May. Since getting my diabetes under control in March (after neglecting my condition for 5 years) I have exercised very rigorously and started eating right. Even with those changes I still will require medicine. From what I can tell most people who progress beyond metformin for treatment and add a second drug to the mix will most often have type 2 issues for life. I now weight 219 pounds and still need to lose another 30 pounds to make my cardio happy. Even then both my primary care doctor and my cardio don't think I will be off the meds.

tjbessey

Jasp
New Member


Date Joined Dec 2009
Total Posts : 6
   Posted 12/24/2009 8:47 AM (GMT -7)   
Thank you! Happy Holidays to you and your family.

Yaya
New Member


Date Joined Feb 2010
Total Posts : 3
   Posted 2/26/2010 2:38 PM (GMT -7)   
Hi everybody
I'm new, in regard to Byetta...they have a website that answers loads of your questions. Go toByetta.com
Yaya

tjbessey
Regular Member


Date Joined Feb 2009
Total Posts : 65
   Posted 2/28/2010 7:28 PM (GMT -7)   
Yaya,
 
Most drugs have great websites. Unfortunately many diabetics like to discuss different medical options with people who have used the drugs that are being discussed. I have noticed you referencing the byetta site on two different threads. In fact I am becoming suspicious that you are actually a mole for the company. We are aware the byetta site exists. Thanks for making us aware.
 
tj

LanieG
Forum Moderator


Date Joined Nov 2006
Total Posts : 5404
   Posted 3/1/2010 5:52 AM (GMT -7)   
We'll keep a lookout for that.  Thanks.  I'm sure there would be no more need for him to mention the website at this point.


Lanie
 
forum moderator - diabetes
diabetes controlled so far by exercise and a low/no carb diet

Post Edited (LanieG) : 3/1/2010 7:00:17 AM (GMT-7)

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