The first thing you and Keith have to do is ask your GP for a referral to an Endocrinologist. These guys/gals specialize in diabetes and they will give you much better advice than your GP. Insulin is the drug of last resort for a type two and Keith is probably a long way from that.
Read Jeannie143's post on Type2 Meds. It has lots of information on glicazide and other drugs. I take "glipazide" as well as metformin. I also take avandia, another very powerful drug to break down my insulin resistence. The point being, there are many combinations of oral meds Keith can try to get back on track. There is also BYETTA, a new injectible you use with or sometimes in place of your metformin that has all kinds of advantages. You should talk over these choices with an Endo specialist after reading here and becoming informed. Type2 Meds
Also it is very important that if Keith has become a semi couch potato and let his physical activity slip he should get out and do something to get back in shape...this helps both the mental and the diabetes enormously.
In any event, failing with metformin is something many of us have experienced and it just happens over time. What happens is you need to add more oral meds.
PS - if you dont' have a blood glucose monitor, buy one and use it!
PPS - Metformin is usually only prescribed for X2 a day so check your dosages...Max should be 2000mg / day
Post Edited (Warren) : 1/11/2006 4:44:31 PM (GMT-7)