Well, I've been using Apidra for one week and it's amazing. It's starts and peaks much faster than Novolog or Humalog. The OptiClik pen (which is the only delivery device for Apidra insulin thus far) is a pain in the --- compared to the prefilled Novolog FlexPen (they over-engineered the OptiClik -- it's bulky, more complicated than it needs to be, and weighs twice as much as the FlexPen), but it's worth the effort because the Apidra makes the bolus so much more effective. Today I took it 15 minutes after a meal and didn't go over my post-meal target an hour later. Major improvement in the bolus regimen IMO. I haven't had a reaction yet, so I'm reserving total judgement until I can get a better feel for crashes. I wouldn't trade Novolog for the old Regular for lots of reasons, not just how fast it works. Apidra is fast on the uptake for sure -- but I want to see how it handles around the curves and how fast the downhill is.